Glen RC - Search Results

1

G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic.

Ingwersen T, Linnenberg C, D'Acunto E, Temori S, Paolucci I, Wasilewski D, Mohammadi B, Kirchmair J, Glen RC, Miranda E, Glatzel M, Galliciotti G. Ingwersen T, et al. Among authors: glen rc. Sci Rep. 2021 Apr 22;11(1):8766. doi: 10.1038/s41598-021-88090-1. Sci Rep. 2021. PMID: 33888787 Free PMC article.

2

Predicting drug metabolism: experiment and/or computation?

Kirchmair J, Göller AH, Lang D, Kunze J, Testa B, Wilson ID, Glen RC, Schneider G. Kirchmair J, et al. Among authors: glen rc. Nat Rev Drug Discov. 2015 Jun;14(6):387-404. doi: 10.1038/nrd4581. Epub 2015 Apr 24. Nat Rev Drug Discov. 2015. PMID: 25907346 Free article. Review.

3

Computational prediction of metabolism: sites, products, SAR, P450 enzyme dynamics, and mechanisms.

Kirchmair J, Williamson MJ, Tyzack JD, Tan L, Bond PJ, Bender A, Glen RC. Kirchmair J, et al. Among authors: glen rc. J Chem Inf Model. 2012 Mar 26;52(3):617-48. doi: 10.1021/ci200542m. Epub 2012 Feb 17. J Chem Inf Model. 2012. PMID: 22339582 Free PMC article. Review.

4

Cytochrome P450 site of metabolism prediction from 2D topological fingerprints using GPU accelerated probabilistic classifiers.

Tyzack JD, Mussa HY, Williamson MJ, Kirchmair J, Glen RC. Tyzack JD, et al. Among authors: glen rc. J Cheminform. 2014 May 27;6:29. doi: 10.1186/1758-2946-6-29. eCollection 2014. J Cheminform. 2014. PMID: 24959208 Free PMC article.

5

FAst MEtabolizer (FAME): A rapid and accurate predictor of sites of metabolism in multiple species by endogenous enzymes.

Kirchmair J, Williamson MJ, Afzal AM, Tyzack JD, Choy AP, Howlett A, Rydberg P, Glen RC. Kirchmair J, et al. Among authors: glen rc. J Chem Inf Model. 2013 Nov 25;53(11):2896-907. doi: 10.1021/ci400503s. Epub 2013 Nov 12. J Chem Inf Model. 2013. PMID: 24219364

6

Molecular mechanism of a specific capsid binder resistance caused by mutations outside the binding pocket.

Braun H, Kirchmair J, Williamson MJ, Makarov VA, Riabova OB, Glen RC, Sauerbrei A, Schmidtke M. Braun H, et al. Among authors: glen rc. Antiviral Res. 2015 Nov;123:138-45. doi: 10.1016/j.antiviral.2015.09.009. Epub 2015 Sep 25. Antiviral Res. 2015. PMID: 26391975 Free article.

7

Anti-cancer drug development: computational strategies to identify and target proteins involved in cancer metabolism.

Mak L, Liggi S, Tan L, Kusonmano K, Rollinger JM, Koutsoukas A, Glen RC, Kirchmair J. Mak L, et al. Among authors: glen rc. Curr Pharm Des. 2013;19(4):532-77. Curr Pharm Des. 2013. PMID: 23016852 Review.

8

A Bone Morphogenetic Protein (BMP)-derived Peptide Based on the Type I Receptor-binding Site Modifies Cell-type Dependent BMP Signalling.

Tong Z, Guo J, Glen RC, Morrell NW, Li W. Tong Z, et al. Among authors: glen rc. Sci Rep. 2019 Sep 17;9(1):13446. doi: 10.1038/s41598-019-49758-x. Sci Rep. 2019. PMID: 31530856 Free PMC article.

9

How do metabolites differ from their parent molecules and how are they excreted?

Kirchmair J, Howlett A, Peironcely JE, Murrell DS, Williamson MJ, Adams SE, Hankemeier T, van Buren L, Duchateau G, Klaffke W, Glen RC. Kirchmair J, et al. Among authors: glen rc. J Chem Inf Model. 2013 Feb 25;53(2):354-67. doi: 10.1021/ci300487z. Epub 2013 Jan 25. J Chem Inf Model. 2013. PMID: 23351040

10

From in silico target prediction to multi-target drug design: current databases, methods and applications.

Koutsoukas A, Simms B, Kirchmair J, Bond PJ, Whitmore AV, Zimmer S, Young MP, Jenkins JL, Glick M, Glen RC, Bender A. Koutsoukas A, et al. Among authors: glen rc. J Proteomics. 2011 Nov 18;74(12):2554-74. doi: 10.1016/j.jprot.2011.05.011. Epub 2011 May 18. J Proteomics. 2011. PMID: 21621023 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

132 results

Search Page

Filters