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Page 1
RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways.
Gudiño V, Pohl SÖ, Billard CV, Cammareri P, Bolado A, Aitken S, Stevenson D, Hall AE, Agostino M, Cassidy J, Nixon C, von Kriegsheim A, Freile P, Popplewell L, Dickson G, Murphy L, Wheeler A, Dunlop M, Din F, Strathdee D, Sansom OJ, Myant KB. Gudiño V, et al. Among authors: stevenson d. Nat Commun. 2021 Apr 20;12(1):2335. doi: 10.1038/s41467-021-22531-3. Nat Commun. 2021. PMID: 33879799 Free PMC article.
Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression.
Li A, Ma Y, Yu X, Mort RL, Lindsay CR, Stevenson D, Strathdee D, Insall RH, Chernoff J, Snapper SB, Jackson IJ, Larue L, Sansom OJ, Machesky LM. Li A, et al. Among authors: stevenson d. Dev Cell. 2011 Oct 18;21(4):722-34. doi: 10.1016/j.devcel.2011.07.008. Epub 2011 Sep 15. Dev Cell. 2011. PMID: 21924960 Free PMC article.
Mouse Tafazzin Is Required for Male Germ Cell Meiosis and Spermatogenesis.
Cadalbert LC, Ghaffar FN, Stevenson D, Bryson S, Vaz FM, Gottlieb E, Strathdee D. Cadalbert LC, et al. Among authors: stevenson d. PLoS One. 2015 Jun 26;10(6):e0131066. doi: 10.1371/journal.pone.0131066. eCollection 2015. PLoS One. 2015. PMID: 26114544 Free PMC article.
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.
Cardaci S, Zheng L, MacKay G, van den Broek NJ, MacKenzie ED, Nixon C, Stevenson D, Tumanov S, Bulusu V, Kamphorst JJ, Vazquez A, Fleming S, Schiavi F, Kalna G, Blyth K, Strathdee D, Gottlieb E. Cardaci S, et al. Among authors: stevenson d. Nat Cell Biol. 2015 Oct;17(10):1317-26. doi: 10.1038/ncb3233. Epub 2015 Aug 24. Nat Cell Biol. 2015. PMID: 26302408 Free PMC article.
CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma.
Walton J, Blagih J, Ennis D, Leung E, Dowson S, Farquharson M, Tookman LA, Orange C, Athineos D, Mason S, Stevenson D, Blyth K, Strathdee D, Balkwill FR, Vousden K, Lockley M, McNeish IA. Walton J, et al. Among authors: stevenson d. Cancer Res. 2016 Oct 15;76(20):6118-6129. doi: 10.1158/0008-5472.CAN-16-1272. Epub 2016 Aug 16. Cancer Res. 2016. PMID: 27530326 Free PMC article.
A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.
Nobis M, Herrmann D, Warren SC, Kadir S, Leung W, Killen M, Magenau A, Stevenson D, Lucas MC, Reischmann N, Vennin C, Conway JRW, Boulghourjian A, Zaratzian A, Law AM, Gallego-Ortega D, Ormandy CJ, Walters SN, Grey ST, Bailey J, Chtanova T, Quinn JMW, Baldock PA, Croucher PI, Schwarz JP, Mrowinska A, Zhang L, Herzog H, Masedunskas A, Hardeman EC, Gunning PW, Del Monte-Nieto G, Harvey RP, Samuel MS, Pajic M, McGhee EJ, Johnsson AE, Sansom OJ, Welch HCE, Morton JP, Strathdee D, Anderson KI, Timpson P. Nobis M, et al. Among authors: stevenson d. Cell Rep. 2017 Oct 3;21(1):274-288. doi: 10.1016/j.celrep.2017.09.022. Cell Rep. 2017. PMID: 28978480 Free article.
Loss of tafazzin results in decreased myoblast differentiation in C2C12 cells: A myoblast model of Barth syndrome and cardiolipin deficiency.
Lou W, Reynolds CA, Li Y, Liu J, Hüttemann M, Schlame M, Stevenson D, Strathdee D, Greenberg ML. Lou W, et al. Among authors: stevenson d. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Aug;1863(8):857-865. doi: 10.1016/j.bbalip.2018.04.015. Epub 2018 Apr 22. Biochim Biophys Acta Mol Cell Biol Lipids. 2018. PMID: 29694924 Free PMC article.
Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas.
Liko D, Mitchell L, Campbell KJ, Ridgway RA, Jones C, Dudek K, King A, Bryson S, Stevenson D, Blyth K, Strathdee D, Morton JP, Bird TG, Knight JRP, Willis AE, Sansom OJ. Liko D, et al. Among authors: stevenson d. Cell Death Differ. 2019 Dec;26(12):2535-2550. doi: 10.1038/s41418-019-0316-7. Epub 2019 Mar 11. Cell Death Differ. 2019. PMID: 30858608 Free PMC article.
Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice.
Humpton TJ, Nomura K, Weber J, Magnussen HM, Hock AK, Nixon C, Dhayade S, Stevenson D, Huang DT, Strathdee D, Blyth K, Vousden KH. Humpton TJ, et al. Among authors: stevenson d. Genes Dev. 2021 Jan 1;35(1-2):117-132. doi: 10.1101/gad.341875.120. Epub 2020 Dec 17. Genes Dev. 2021. PMID: 33334825 Free PMC article.
2,068 results