Li S - Search Results

1

Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C.

Roney JC, Li S, Farfel-Becker T, Huang N, Sun T, Xie Y, Cheng XT, Lin MY, Platt FM, Sheng ZH. Roney JC, et al. Among authors: li s. Dev Cell. 2021 May 17;56(10):1452-1468.e8. doi: 10.1016/j.devcel.2021.03.032. Epub 2021 Apr 19. Dev Cell. 2021. PMID: 33878344 Free PMC article.

2

Neuronal Soma-Derived Degradative Lysosomes Are Continuously Delivered to Distal Axons to Maintain Local Degradation Capacity.

Farfel-Becker T, Roney JC, Cheng XT, Li S, Cuddy SR, Sheng ZH. Farfel-Becker T, et al. Among authors: li s. Cell Rep. 2019 Jul 2;28(1):51-64.e4. doi: 10.1016/j.celrep.2019.06.013. Cell Rep. 2019. PMID: 31269450 Free PMC article.

3

The secret life of degradative lysosomes in axons: delivery from the soma, enzymatic activity, and local autophagic clearance.

Farfel-Becker T, Roney JC, Cheng XT, Li S, Cuddy SR, Sheng ZH. Farfel-Becker T, et al. Among authors: li s. Autophagy. 2020 Jan;16(1):167-168. doi: 10.1080/15548627.2019.1669869. Epub 2019 Sep 23. Autophagy. 2020. PMID: 31533518 Free PMC article. Review.

4

Defects in syntabulin-mediated synaptic cargo transport associate with autism-like synaptic dysfunction and social behavioral traits.

Xiong GJ, Cheng XT, Sun T, Xie Y, Huang N, Li S, Lin MY, Sheng ZH. Xiong GJ, et al. Among authors: li s. Mol Psychiatry. 2021 May;26(5):1472-1490. doi: 10.1038/s41380-020-0713-9. Epub 2020 Apr 24. Mol Psychiatry. 2021. PMID: 32332993 Free PMC article.

5

The cross-talk of energy sensing and mitochondrial anchoring sustains synaptic efficacy by maintaining presynaptic metabolism.

Li S, Xiong GJ, Huang N, Sheng ZH. Li S, et al. Nat Metab. 2020 Oct;2(10):1077-1095. doi: 10.1038/s42255-020-00289-0. Epub 2020 Oct 5. Nat Metab. 2020. PMID: 33020662 Free PMC article.

6

Lipid-mediated impairment of axonal lysosome transport contributing to autophagic stress.

Roney JC, Li S, Farfel-Becker T, Huang N, Sun T, Xie Y, Cheng XT, Lin MY, Platt FM, Sheng ZH. Roney JC, et al. Among authors: li s. Autophagy. 2021 Jul;17(7):1796-1798. doi: 10.1080/15548627.2021.1938916. Epub 2021 Jun 30. Autophagy. 2021. PMID: 34085599 Free PMC article.

7

Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia.

Huang N, Li S, Xie Y, Han Q, Xu XM, Sheng ZH. Huang N, et al. Among authors: li s. Curr Biol. 2021 Jul 26;31(14):3098-3114.e7. doi: 10.1016/j.cub.2021.04.079. Epub 2021 Jun 3. Curr Biol. 2021. PMID: 34087103 Free PMC article.

8

Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2.

Chamberlain KA, Huang N, Xie Y, LiCausi F, Li S, Li Y, Sheng ZH. Chamberlain KA, et al. Among authors: li s, li y. Neuron. 2021 Nov 3;109(21):3456-3472.e8. doi: 10.1016/j.neuron.2021.08.011. Epub 2021 Sep 9. Neuron. 2021. PMID: 34506725 Free PMC article.

9

Energy matters: presynaptic metabolism and the maintenance of synaptic transmission.

Li S, Sheng ZH. Li S, et al. Nat Rev Neurosci. 2022 Jan;23(1):4-22. doi: 10.1038/s41583-021-00535-8. Epub 2021 Nov 15. Nat Rev Neurosci. 2022. PMID: 34782781 Review.

10

Oligodendrocyte-derived transcellular signaling regulates axonal energy metabolism.

Li S, Sheng ZH. Li S, et al. Curr Opin Neurobiol. 2023 Jun;80:102722. doi: 10.1016/j.conb.2023.102722. Epub 2023 Apr 5. Curr Opin Neurobiol. 2023. PMID: 37028201 Free PMC article. Review.

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