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Inhibiting autophagy targets human leukemic stem cells and hypoxic AML blasts by disrupting mitochondrial homeostasis.
Blood Adv. 2021 Apr 27;5(8):2087-2100. doi: 10.1182/bloodadvances.2020002666.
Blood Adv. 2021.
PMID: 33877295
Free PMC article.
Autophagy inhibition induces AML cell death and enhances the efficacy of chemotherapy under hypoxia.
Wang ES, Fay HRS, Dykstra KM, Phelps MN, Johnson M, Harrigan A, Giorgi MC.
Wang ES, et al. Among authors: fay hrs.
bioRxiv [Preprint]. 2024 Nov 26:2024.11.24.625107. doi: 10.1101/2024.11.24.625107.
bioRxiv. 2024.
PMID: 39651164
Free PMC article.
Preprint.
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The NSD2 p.E1099K Mutation Is Enriched at Relapse and Confers Drug Resistance in a Cell Context-Dependent Manner in Pediatric Acute Lymphoblastic Leukemia.
Pierro J, Saliba J, Narang S, Sethia G, Saint Fleur-Lominy S, Chowdhury A, Qualls A, Fay H, Kilberg HL, Moriyama T, Fuller TJ, Teachey DT, Schmiegelow K, Yang JJ, Loh ML, Brown PA, Zhang J, Ma X, Tsirigos A, Evensen NA, Carroll WL.
Pierro J, et al.
Mol Cancer Res. 2020 Aug;18(8):1153-1165. doi: 10.1158/1541-7786.MCR-20-0092. Epub 2020 Apr 24.
Mol Cancer Res. 2020.
PMID: 32332049
Free PMC article.
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