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Page 1
Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein.
Davies N, Hovdal D, Edmunds N, Nordberg P, Dahlén A, Dabkowska A, Arteta MY, Radulescu A, Kjellman T, Höijer A, Seeliger F, Holmedal E, Andihn E, Bergenhem N, Sandinge AS, Johansson C, Hultin L, Johansson M, Lindqvist J, Björsson L, Jing Y, Bartesaghi S, Lindfors L, Andersson S. Davies N, et al. Among authors: radulescu a. Mol Ther Nucleic Acids. 2021 Mar 13;24:369-384. doi: 10.1016/j.omtn.2021.03.008. eCollection 2021 Jun 4. Mol Ther Nucleic Acids. 2021. PMID: 33868782 Free PMC article.
Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles.
Yanez Arteta M, Kjellman T, Bartesaghi S, Wallin S, Wu X, Kvist AJ, Dabkowska A, Székely N, Radulescu A, Bergenholtz J, Lindfors L. Yanez Arteta M, et al. Among authors: radulescu a. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3351-E3360. doi: 10.1073/pnas.1720542115. Epub 2018 Mar 27. Proc Natl Acad Sci U S A. 2018. PMID: 29588418 Free PMC article.
Hybrid Biopolymer and Lipid Nanoparticles with Improved Transfection Efficacy for mRNA.
Siewert CD, Haas H, Cornet V, Nogueira SS, Nawroth T, Uebbing L, Ziller A, Al-Gousous J, Radulescu A, Schroer MA, Blanchet CE, Svergun DI, Radsak MP, Sahin U, Langguth P. Siewert CD, et al. Among authors: radulescu a. Cells. 2020 Sep 5;9(9):2034. doi: 10.3390/cells9092034. Cells. 2020. PMID: 32899484 Free PMC article.
Investigation of charge ratio variation in mRNA - DEAE-dextran polyplex delivery systems.
Siewert C, Haas H, Nawroth T, Ziller A, Nogueira SS, Schroer MA, Blanchet CE, Svergun DI, Radulescu A, Bates F, Huesemann Y, Radsak MP, Sahin U, Langguth P. Siewert C, et al. Among authors: radulescu a. Biomaterials. 2019 Feb;192:612-620. doi: 10.1016/j.biomaterials.2018.10.020. Epub 2018 Nov 17. Biomaterials. 2019. PMID: 30502967 Free article.
Tuning the instrument resolution using chopper and time of flight at the small-angle neutron scattering diffractometer KWS-2.
Radulescu A, Székely NK, Polachowski S, Leyendecker M, Amann M, Buitenhuis J, Drochner M, Engels R, Hanslik R, Kemmerling G, Lindner P, Papagiannopoulos A, Pipich V, Willner L, Frielinghaus H, Richter D. Radulescu A, et al. J Appl Crystallogr. 2015 Nov 19;48(Pt 6):1849-1859. doi: 10.1107/S1600576715019019. eCollection 2015 Dec 1. J Appl Crystallogr. 2015. PMID: 26664343 Free PMC article.
320 results