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Human challenge study with a Shigella bioconjugate vaccine: Analyses of clinical efficacy and correlate of protection.
Talaat KR, Alaimo C, Martin P, Bourgeois AL, Dreyer AM, Kaminski RW, Porter CK, Chakraborty S, Clarkson KA, Brubaker J, Elwood D, Frölich R, DeNearing B, Weerts H, Feijoo BL, Halpern J, Sack D, Riddle MS, Fonck VG. Talaat KR, et al. EBioMedicine. 2021 Apr;66:103310. doi: 10.1016/j.ebiom.2021.103310. Epub 2021 Apr 13. EBioMedicine. 2021. PMID: 33862589 Free PMC article. Clinical Trial.
An open-label phase I trial of a live attenuated H2N2 influenza virus vaccine in healthy adults.
Talaat KR, Karron RA, Liang PH, McMahon BA, Luke CJ, Thumar B, Chen GL, Min JY, Lamirande EW, Jin H, Coelingh KL, Kemble GW, Subbarao K. Talaat KR, et al. Influenza Other Respir Viruses. 2013 Jan;7(1):66-73. doi: 10.1111/j.1750-2659.2012.00350.x. Epub 2012 Mar 14. Influenza Other Respir Viruses. 2013. PMID: 22417012 Free PMC article. Clinical Trial.
A single dose of any of four different live attenuated tetravalent dengue vaccines is safe and immunogenic in flavivirus-naive adults: a randomized, double-blind clinical trial.
Durbin AP, Kirkpatrick BD, Pierce KK, Elwood D, Larsson CJ, Lindow JC, Tibery C, Sabundayo BP, Shaffer D, Talaat KR, Hynes NA, Wanionek K, Carmolli MP, Luke CJ, Murphy BR, Subbarao K, Whitehead SS. Durbin AP, et al. Among authors: talaat kr. J Infect Dis. 2013 Mar 15;207(6):957-65. doi: 10.1093/infdis/jis936. Epub 2013 Jan 17. J Infect Dis. 2013. PMID: 23329850 Free PMC article. Clinical Trial.
The live attenuated dengue vaccine TV003 elicits complete protection against dengue in a human challenge model.
Kirkpatrick BD, Whitehead SS, Pierce KK, Tibery CM, Grier PL, Hynes NA, Larsson CJ, Sabundayo BP, Talaat KR, Janiak A, Carmolli MP, Luke CJ, Diehl SA, Durbin AP. Kirkpatrick BD, et al. Among authors: talaat kr. Sci Transl Med. 2016 Mar 16;8(330):330ra36. doi: 10.1126/scitranslmed.aaf1517. Epub 2016 Mar 16. Sci Transl Med. 2016. PMID: 27089205 Clinical Trial.
Rifaximin Fails to Prevent Campylobacteriosis in the Human Challenge Model: A Randomized, Double-Blind, Placebo-Controlled Trial.
Rimmer JE, Harro C, Sack DA, Talaat KR, Gutierrez RL, DeNearing B, Brubaker J, Laird RM, Poly F, Maue AC, Jaep K, Alcala A, Mochalova Y, Gariepy CL, Chakraborty S, Guerry P, Tribble DR, Porter CK, Riddle MS. Rimmer JE, et al. Among authors: talaat kr. Clin Infect Dis. 2018 Apr 17;66(9):1435-1441. doi: 10.1093/cid/cix1014. Clin Infect Dis. 2018. PMID: 29145631 Clinical Trial.
Campylobacter jejuni transcriptional and genetic adaptation during human infection.
Crofts AA, Poly FM, Ewing CP, Kuroiwa JM, Rimmer JE, Harro C, Sack D, Talaat KR, Porter CK, Gutierrez RL, DeNearing B, Brubaker J, Laird RM, Maue AC, Jaep K, Alcala A, Tribble DR, Riddle MS, Ramakrishnan A, McCoy AJ, Davies BW, Guerry P, Trent MS. Crofts AA, et al. Among authors: talaat kr. Nat Microbiol. 2018 Apr;3(4):494-502. doi: 10.1038/s41564-018-0133-7. Epub 2018 Mar 27. Nat Microbiol. 2018. PMID: 29588538 Free PMC article.
Enterotoxigenic E. coli virulence gene regulation in human infections.
Crofts AA, Giovanetti SM, Rubin EJ, Poly FM, Gutiérrez RL, Talaat KR, Porter CK, Riddle MS, DeNearing B, Brubaker J, Maciel M Jr, Alcala AN, Chakraborty S, Prouty MG, Savarino SJ, Davies BW, Trent MS. Crofts AA, et al. Among authors: talaat kr. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8968-E8976. doi: 10.1073/pnas.1808982115. Epub 2018 Aug 20. Proc Natl Acad Sci U S A. 2018. PMID: 30126994 Free PMC article. Clinical Trial.
The way forward for ETEC controlled human infection models (CHIMs).
Hanevik K, Chen WH, Talaat KR, Porter C, Bourgeois L. Hanevik K, et al. Among authors: talaat kr. Vaccine. 2019 Aug 7;37(34):4794-4799. doi: 10.1016/j.vaccine.2019.01.003. Epub 2019 Jan 29. Vaccine. 2019. PMID: 30709728 Free article. Review.
70 results