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Page 1
Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo.
Tan T, Wu J, Si C, Dai S, Zhang Y, Sun N, Zhang E, Shao H, Si W, Yang P, Wang H, Chen Z, Zhu R, Kang Y, Hernandez-Benitez R, Martinez Martinez L, Nuñez Delicado E, Berggren WT, Schwarz M, Ai Z, Li T, Rodriguez Esteban C, Ji W, Niu Y, Izpisua Belmonte JC. Tan T, et al. Cell. 2021 Apr 15;184(8):2020-2032.e14. doi: 10.1016/j.cell.2021.03.020. Cell. 2021. PMID: 33861963 Free article.
Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction.
Suzuki K, Yamamoto M, Hernandez-Benitez R, Li Z, Wei C, Soligalla RD, Aizawa E, Hatanaka F, Kurita M, Reddy P, Ocampo A, Hishida T, Sakurai M, Nemeth AN, Nuñez Delicado E, Campistol JM, Magistretti P, Guillen P, Rodriguez Esteban C, Gong J, Yuan Y, Gu Y, Liu GH, López-Otín C, Wu J, Zhang K, Izpisua Belmonte JC. Suzuki K, et al. Cell Res. 2019 Oct;29(10):804-819. doi: 10.1038/s41422-019-0213-0. Epub 2019 Aug 23. Cell Res. 2019. PMID: 31444470 Free PMC article.
First progeria monkey model generated using base editor.
Reddy P, Shao Y, Hernandez-Benitez R, Nuñez Delicado E, Izpisua Belmonte JC. Reddy P, et al. Protein Cell. 2020 Dec;11(12):862-865. doi: 10.1007/s13238-020-00765-z. Protein Cell. 2020. PMID: 32729023 Free PMC article. Review. No abstract available.
Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo.
Tan T, Wu J, Si C, Dai S, Zhang Y, Sun N, Zhang E, Shao H, Si W, Yang P, Wang H, Chen Z, Zhu R, Kang Y, Hernandez-Benitez R, Martinez Martinez L, Nuñez Delicado E, Berggren WT, Schwarz M, Ai Z, Li T, Deng H, Esteban CR, Ji W, Niu Y, Izpisua Belmonte JC. Tan T, et al. Cell. 2021 Jun 24;184(13):3589. doi: 10.1016/j.cell.2021.06.011. Cell. 2021. PMID: 34171321 Free article. No abstract available.
In vivo reprogramming of wound-resident cells generates skin epithelial tissue.
Kurita M, Araoka T, Hishida T, O'Keefe DD, Takahashi Y, Sakamoto A, Sakurai M, Suzuki K, Wu J, Yamamoto M, Hernandez-Benitez R, Ocampo A, Reddy P, Shokhirev MN, Magistretti P, Núñez Delicado E, Eto H, Harii K, Izpisua Belmonte JC. Kurita M, et al. Nature. 2018 Sep;561(7722):243-247. doi: 10.1038/s41586-018-0477-4. Epub 2018 Sep 5. Nature. 2018. PMID: 30185909 Free PMC article.
In vivo partial cellular reprogramming enhances liver plasticity and regeneration.
Hishida T, Yamamoto M, Hishida-Nozaki Y, Shao C, Huang L, Wang C, Shojima K, Xue Y, Hang Y, Shokhirev M, Memczak S, Sahu SK, Hatanaka F, Ros RR, Maxwell MB, Chavez J, Shao Y, Liao HK, Martinez-Redondo P, Guillen-Guillen I, Hernandez-Benitez R, Esteban CR, Qu J, Holmes MC, Yi F, Hickey RD, Garcia PG, Delicado EN, Castells A, Campistol JM, Yu Y, Hargreaves DC, Asai A, Reddy P, Liu GH, Izpisua Belmonte JC. Hishida T, et al. Among authors: hernandez benitez r. Cell Rep. 2022 Apr 26;39(4):110730. doi: 10.1016/j.celrep.2022.110730. Cell Rep. 2022. PMID: 35476977 Free PMC article.
At the Heart of Genome Editing and Cardiovascular Diseases.
Hernandez-Benitez R, Martinez-Martinez ML, Lajara J, Magistretti P, Montserrat N, Izpisua Belmonte JC. Hernandez-Benitez R, et al. Circ Res. 2018 Jul 6;123(2):221-223. doi: 10.1161/CIRCRESAHA.118.312676. Circ Res. 2018. PMID: 29976689 Review. No abstract available.
In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration.
Suzuki K, Tsunekawa Y, Hernandez-Benitez R, Wu J, Zhu J, Kim EJ, Hatanaka F, Yamamoto M, Araoka T, Li Z, Kurita M, Hishida T, Li M, Aizawa E, Guo S, Chen S, Goebl A, Soligalla RD, Qu J, Jiang T, Fu X, Jafari M, Esteban CR, Berggren WT, Lajara J, Nuñez-Delicado E, Guillen P, Campistol JM, Matsuzaki F, Liu GH, Magistretti P, Zhang K, Callaway EM, Zhang K, Belmonte JC. Suzuki K, et al. Nature. 2016 Dec 1;540(7631):144-149. doi: 10.1038/nature20565. Epub 2016 Nov 16. Nature. 2016. PMID: 27851729 Free PMC article.
αKLOTHO and sTGFβR2 treatment counteract the osteoarthritic phenotype developed in a rat model.
Martinez-Redondo P, Guillen-Guillen I, Davidsohn N, Wang C, Prieto J, Kurita M, Hatanaka F, Zhong C, Hernandez-Benitez R, Hishida T, Lezaki T, Sakamoto A, Nemeth AN, Hishida Y, Esteban CR, Shojima K, Huang L, Shokhirev M, Nuñez-Delicado E, Campistol JM, Guillen-Vicente I, Rodriguez-Iñigo E, Lopez-Alcorocho JM, Guillen-Vicente M, Church G, Reddy P, Guillen-Garcia P, Liu GH, Belmonte JCI. Martinez-Redondo P, et al. Protein Cell. 2020 Mar;11(3):219-226. doi: 10.1007/s13238-019-00685-7. Protein Cell. 2020. PMID: 31950348 Free PMC article. No abstract available.
40 results