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Page 1
Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques.
King HAD, Gordon Joyce M, Naouar IE, Ahmed A, Cincotta CM, Subra C, Peachman KK, Hack HH, Chen RE, Thomas PV, Chen WH, Sankhala RS, Hajduczki A, Martinez EJ, Peterson CE, Chang WC, Choe M, Smith C, Headley JA, Elyard HA, Cook A, Anderson A, Wuertz KM, Dong M, Swafford I, Case JB, Currier JR, Lal KG, Amare MF, Dussupt V, Molnar S, Daye SP, Zeng X, Barkei EK, Alfson K, Staples HM, Carrion R, Krebs SJ, Paquin-Proulx D, Karasavvas N, Polonis VR, Jagodzinski LL, Vasan S, Scott PT, Huang Y, Nair MS, Ho DD, de Val N, Diamond MS, Lewis MG, Rao M, Matyas GR, Gromowski GD, Peel SA, Michael NL, Modjarrad K, Bolton DL. King HAD, et al. Among authors: ho dd. bioRxiv [Preprint]. 2021 Apr 10:2021.04.09.439166. doi: 10.1101/2021.04.09.439166. bioRxiv. 2021. Update in: Proc Natl Acad Sci U S A. 2021 Sep 21;118(38):e2106433118. doi: 10.1073/pnas.2106433118 PMID: 33851155 Free PMC article. Updated. Preprint.
Efficacy of a Broadly Neutralizing SARS-CoV-2 Ferritin Nanoparticle Vaccine in Nonhuman Primates.
Joyce MG, King HAD, Naouar IE, Ahmed A, Peachman KK, Cincotta CM, Subra C, Chen RE, Thomas PV, Chen WH, Sankhala RS, Hajduczki A, Martinez EJ, Peterson CE, Chang WC, Choe M, Smith C, Lee PJ, Headley JA, Taddese MG, Elyard HA, Cook A, Anderson A, McGuckin-Wuertz K, Dong M, Swafford I, Case JB, Currier JR, Lal KG, O'Connell RJ, Molnar S, Nair MS, Dussupt V, Daye SP, Zeng X, Barkei EK, Staples HM, Alfson K, Carrion R, Krebs SJ, Paquin-Proulx D, Karasavva N, Polonis VR, Jagodzinski LL, Amare MF, Vasan S, Scott PT, Huang Y, Ho DD, de Val N, Diamond MS, Lewis MG, Rao M, Matyas GR, Gromowski GD, Peel SA, Michael NL, Bolton DL, Modjarrad K. Joyce MG, et al. Among authors: ho dd. bioRxiv [Preprint]. 2021 Mar 25:2021.03.24.436523. doi: 10.1101/2021.03.24.436523. bioRxiv. 2021. PMID: 33791694 Free PMC article. Preprint.
Antibodies that neutralize all current SARS-CoV-2 variants of concern by conformational locking.
Liu L, Casner RG, Guo Y, Wang Q, Iketani S, Chan JF, Yu J, Dadonaite B, Nair MS, Mohri H, Reddem ER, Yuan S, Poon VK, Chan CC, Yuen KY, Sheng Z, Huang Y, Bloom JD, Shapiro L, Ho DD. Liu L, et al. Among authors: ho dd. bioRxiv [Preprint]. 2023 Apr 10:2023.04.08.536123. doi: 10.1101/2023.04.08.536123. bioRxiv. 2023. PMID: 37090592 Free PMC article. Preprint.
Potent neutralization by a receptor binding domain monoclonal antibody with broad specificity for SARS-CoV-2 JN.1 and other variants.
Piepenbrink MS, Khalil AM, Chang A, Mostafa A, Basu M, Sarkar S, Panjwani S, Ha YH, Ma Y, Ye C, Wang Q, Green TJ, Kizziah JL, Erdmann NB, Goepfert PA, Liu L, Ho DD, Martinez-Sobrido L, Walter MR, Kobie JJ. Piepenbrink MS, et al. Among authors: ho dd. bioRxiv [Preprint]. 2024 Apr 29:2024.04.27.591446. doi: 10.1101/2024.04.27.591446. bioRxiv. 2024. Update in: Npj Viruses. 2024;2(1):55. doi: 10.1038/s44298-024-00063-z PMID: 38746414 Free PMC article. Updated. Preprint.
The Functional Landscape of SARS-CoV-2 3CL Protease.
Iketani S, Hong SJ, Sheng J, Bahari F, Culbertson B, Atanaki FF, Aditham AK, Kratz AF, Luck MI, Tian R, Goff SP, Montazeri H, Sabo Y, Ho DD, Chavez A. Iketani S, et al. Among authors: ho dd. bioRxiv [Preprint]. 2022 Jul 12:2022.06.23.497404. doi: 10.1101/2022.06.23.497404. bioRxiv. 2022. Update in: Cell Host Microbe. 2022 Oct 12;30(10):1354-1362.e6. doi: 10.1016/j.chom.2022.08.003 PMID: 35860222 Free PMC article. Updated. Preprint.
Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir.
Iketani S, Mohri H, Culbertson B, Hong SJ, Duan Y, Luck MI, Annavajhala MK, Guo Y, Sheng Z, Uhlemann AC, Goff SP, Sabo Y, Yang H, Chavez A, Ho DD. Iketani S, et al. Among authors: ho dd. bioRxiv [Preprint]. 2022 Aug 18:2022.08.07.499047. doi: 10.1101/2022.08.07.499047. bioRxiv. 2022. Update in: Nature. 2023 Jan;613(7944):558-564. doi: 10.1038/s41586-022-05514-2 PMID: 36032976 Free PMC article. Updated. Preprint.
A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike.
Dadonaite B, Crawford KHD, Radford CE, Farrell AG, Yu TC, Hannon WW, Zhou P, Andrabi R, Burton DR, Liu L, Ho DD, Neher RA, Bloom JD. Dadonaite B, et al. Among authors: ho dd. bioRxiv [Preprint]. 2022 Oct 13:2022.10.13.512056. doi: 10.1101/2022.10.13.512056. bioRxiv. 2022. Update in: Cell. 2023 Mar 16;186(6):1263-1278.e20. doi: 10.1016/j.cell.2023.02.001 PMID: 36263061 Free PMC article. Updated. Preprint.
SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2.
Chen S, Yang L, Nilsson-Payant B, Han Y, Jaffré F, Zhu J, Wang P, Zhang T, Redmond D, Houghton S, Møller R, Hoagland D, Horiuchi S, Acklin J, Lim J, Bram Y, Richardson C, Chandar V, Borczuk A, Huang Y, Xiang J, Ho D, Schwartz R, tenOever B, Evans T. Chen S, et al. Res Sq [Preprint]. 2020 Nov 17:rs.3.rs-94634. doi: 10.21203/rs.3.rs-94634/v1. Res Sq. 2020. Update in: Stem Cell Reports. 2021 Sep 14;16(9):2274-2288. doi: 10.1016/j.stemcr.2021.07.012 PMID: 33236003 Free PMC article. Updated. Preprint.
A multiplex method for rapidly identifying viral protease inhibitors.
Hong SJ, Resnick SJ, Iketani S, Cha JW, Albert BA, Fazekas CT, Chang CW, Liu H, Dagan S, Abagyan MR, Fajtová P, Culbertson B, Brace B, Reddem ER, Forouhar F, Glickman JF, Balkovec JM, Stockwell BR, Shapiro L, O'Donoghue AJ, Sabo Y, Freundlich JS, Ho DD, Chavez A. Hong SJ, et al. Among authors: ho dd. Mol Syst Biol. 2025 Jan 6. doi: 10.1038/s44320-024-00082-1. Online ahead of print. Mol Syst Biol. 2025. PMID: 39762652 Free article.
464 results