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mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif.
Baffi TR, Lordén G, Wozniak JM, Feichtner A, Yeung W, Kornev AP, King CC, Del Rio JC, Limaye AJ, Bogomolovas J, Gould CM, Chen J, Kennedy EJ, Kannan N, Gonzalez DJ, Stefan E, Taylor SS, Newton AC. Baffi TR, et al. Among authors: lorden g. Sci Signal. 2021 Apr 13;14(678):eabe4509. doi: 10.1126/scisignal.abe4509. Sci Signal. 2021. PMID: 33850054 Free PMC article.
PHLPP1 counter-regulates STAT1-mediated inflammatory signaling.
Cohen Katsenelson K, Stender JD, Kawashima AT, Lordén G, Uchiyama S, Nizet V, Glass CK, Newton AC. Cohen Katsenelson K, et al. Among authors: lorden g. Elife. 2019 Aug 13;8:e48609. doi: 10.7554/eLife.48609. Elife. 2019. PMID: 31408005 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35553788
PHLPP Signaling in Immune Cells.
Lordén G, Lam AJ, Levings MK, Newton AC. Lordén G, et al. Curr Top Microbiol Immunol. 2022;436:117-143. doi: 10.1007/978-3-031-06566-8_5. Curr Top Microbiol Immunol. 2022. PMID: 36243842 Review.
Lipin-2 regulates NLRP3 inflammasome by affecting P2X7 receptor activation.
Lordén G, Sanjuán-García I, de Pablo N, Meana C, Alvarez-Miguel I, Pérez-García MT, Pelegrín P, Balsinde J, Balboa MA. Lordén G, et al. J Exp Med. 2017 Feb;214(2):511-528. doi: 10.1084/jem.20161452. Epub 2016 Dec 28. J Exp Med. 2017. PMID: 28031477 Free PMC article.
13 results