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Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models.
Sobral LM, Sousa LO, Coletta RD, Cabral H, Greene LJ, Tajara EH, Gutkind JS, Curti C, Leopoldino AM. Sobral LM, et al. Among authors: sousa lo. Mol Cancer. 2014 Feb 20;13:32. doi: 10.1186/1476-4598-13-32. Mol Cancer. 2014. PMID: 24555657 Free PMC article.
SET protein accumulation prevents cell death in head and neck squamous cell carcinoma through regulation of redox state and autophagy.
Ouchida AT, Uyemura VT, Queiroz AL, Brauer VS, Cavalcanti-Neto MP, Sousa LO, Uyemura SA, Curti C, Leopoldino AM. Ouchida AT, et al. Among authors: sousa lo. Biochim Biophys Acta Mol Cell Res. 2019 Apr;1866(4):623-637. doi: 10.1016/j.bbamcr.2019.01.005. Epub 2019 Jan 16. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 30658075 Free article.
Accumulation of sphingosine kinase 2 protein induces malignant transformation in oral keratinocytes associated with stemness, autophagy, senescence, and proliferation.
Fugio LB, Silva G, Ferraz CL, Trevisan GL, Coeli-Lacchini FB, Garcia CB, Sousa LO, Malta TM, Gil CD, Leopoldino AM. Fugio LB, et al. Among authors: sousa lo. Biochim Biophys Acta Mol Cell Res. 2024 Jan;1871(1):119616. doi: 10.1016/j.bbamcr.2023.119616. Epub 2023 Oct 28. Biochim Biophys Acta Mol Cell Res. 2024. PMID: 37898377 Free article.
33 results