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Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2.
Mou H, Quinlan BD, Peng H, Liu G, Guo Y, Peng S, Zhang L, Davis-Gardner ME, Gardner MR, Crynen G, DeVaux LB, Voo ZX, Bailey CC, Alpert MD, Rader C, Gack MU, Choe H, Farzan M. Mou H, et al. Among authors: gardner mr. PLoS Pathog. 2021 Apr 9;17(4):e1009501. doi: 10.1371/journal.ppat.1009501. eCollection 2021 Apr. PLoS Pathog. 2021. PMID: 33836016 Free PMC article.
AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges.
Gardner MR, Kattenhorn LM, Kondur HR, von Schaewen M, Dorfman T, Chiang JJ, Haworth KG, Decker JM, Alpert MD, Bailey CC, Neale ES Jr, Fellinger CH, Joshi VR, Fuchs SP, Martinez-Navio JM, Quinlan BD, Yao AY, Mouquet H, Gorman J, Zhang B, Poignard P, Nussenzweig MC, Burton DR, Kwong PD, Piatak M Jr, Lifson JD, Gao G, Desrosiers RC, Evans DT, Hahn BH, Ploss A, Cannon PM, Seaman MS, Farzan M. Gardner MR, et al. Nature. 2015 Mar 5;519(7541):87-91. doi: 10.1038/nature14264. Epub 2015 Feb 18. Nature. 2015. PMID: 25707797 Free PMC article.
eCD4-Ig promotes ADCC activity of sera from HIV-1-infected patients.
Davis-Gardner ME, Gardner MR, Alfant B, Farzan M. Davis-Gardner ME, et al. Among authors: gardner mr. PLoS Pathog. 2017 Dec 18;13(12):e1006786. doi: 10.1371/journal.ppat.1006786. eCollection 2017 Dec. PLoS Pathog. 2017. PMID: 29253851 Free PMC article.
73 results