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SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation.
Yan B, Freiwald T, Chauss D, Wang L, West E, Mirabelli C, Zhang CJ, Nichols EM, Malik N, Gregory R, Bantscheff M, Ghidelli-Disse S, Kolev M, Frum T, Spence JR, Sexton JZ, Alysandratos KD, Kotton DN, Pittaluga S, Bibby J, Niyonzima N, Olson MR, Kordasti S, Portilla D, Wobus CE, Laurence A, Lionakis MS, Kemper C, Afzali B, Kazemian M. Yan B, et al. Among authors: spence jr. Sci Immunol. 2021 Apr 7;6(58):eabg0833. doi: 10.1126/sciimmunol.abg0833. Sci Immunol. 2021. PMID: 33827897 Free PMC article.
Astrovirus replication in human intestinal enteroids reveals multi-cellular tropism and an intricate host innate immune landscape.
Kolawole AO, Mirabelli C, Hill DR, Svoboda SA, Janowski AB, Passalacqua KD, Rodriguez BN, Dame MK, Freiden P, Berger RP, Vu DL, Hosmillo M, O'Riordan MXD, Schultz-Cherry S, Guix S, Spence JR, Wang D, Wobus CE. Kolawole AO, et al. Among authors: spence jr. PLoS Pathog. 2019 Oct 31;15(10):e1008057. doi: 10.1371/journal.ppat.1008057. eCollection 2019 Oct. PLoS Pathog. 2019. PMID: 31671153 Free PMC article.
Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19.
Mirabelli C, Wotring JW, Zhang CJ, McCarty SM, Fursmidt R, Frum T, Kadambi NS, Amin AT, O'Meara TR, Pretto CD, Spence JR, Huang J, Alysandratos KD, Kotton DN, Handelman SK, Wobus CE, Weatherwax KJ, Mashour GA, O'Meara MJ, Sexton JZ. Mirabelli C, et al. Among authors: spence jr. bioRxiv [Preprint]. 2020 Dec 7:2020.05.27.117184. doi: 10.1101/2020.05.27.117184. bioRxiv. 2020. Update in: Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2105815118. doi: 10.1073/pnas.2105815118 PMID: 32577649 Free PMC article. Updated. Preprint.
Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells.
Hawkins FJ, Suzuki S, Beermann ML, Barillà C, Wang R, Villacorta-Martin C, Berical A, Jean JC, Le Suer J, Matte T, Simone-Roach C, Tang Y, Schlaeger TM, Crane AM, Matthias N, Huang SXL, Randell SH, Wu J, Spence JR, Carraro G, Stripp BR, Rab A, Sorsher EJ, Horani A, Brody SL, Davis BR, Kotton DN. Hawkins FJ, et al. Among authors: spence jr. Cell Stem Cell. 2021 Jan 7;28(1):79-95.e8. doi: 10.1016/j.stem.2020.09.017. Epub 2020 Oct 23. Cell Stem Cell. 2021. PMID: 33098807 Free PMC article.
Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19.
Mirabelli C, Wotring JW, Zhang CJ, McCarty SM, Fursmidt R, Pretto CD, Qiao Y, Zhang Y, Frum T, Kadambi NS, Amin AT, O'Meara TR, Spence JR, Huang J, Alysandratos KD, Kotton DN, Handelman SK, Wobus CE, Weatherwax KJ, Mashour GA, O'Meara MJ, Chinnaiyan AM, Sexton JZ. Mirabelli C, et al. Among authors: spence jr. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2105815118. doi: 10.1073/pnas.2105815118. Proc Natl Acad Sci U S A. 2021. PMID: 34413211 Free PMC article.
217 results