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Clinical Acquired Resistance to KRASG12C Inhibition through a Novel KRAS Switch-II Pocket Mutation and Polyclonal Alterations Converging on RAS-MAPK Reactivation.
Cancer Discov. 2021 Aug;11(8):1913-1922. doi: 10.1158/2159-8290.CD-21-0365. Epub 2021 Apr 6.
Cancer Discov. 2021.
PMID: 33824136
Free PMC article.
KRASG12C-independent feedback activation of wild-type RAS constrains KRASG12C inhibitor efficacy.
Ryan MB, Coker O, Sorokin A, Fella K, Barnes H, Wong E, Kanikarla P, Gao F, Zhang Y, Zhou L, Kopetz S, Corcoran RB.
Ryan MB, et al.
Cell Rep. 2022 Jun 21;39(12):110993. doi: 10.1016/j.celrep.2022.110993.
Cell Rep. 2022.
PMID: 35732135
Free PMC article.
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A Code of Mono-phosphorylation Modulates the Function of RB.
Sanidas I, Morris R, Fella KA, Rumde PH, Boukhali M, Tai EC, Ting DT, Lawrence MS, Haas W, Dyson NJ.
Sanidas I, et al. Among authors: fella ka.
Mol Cell. 2019 Mar 7;73(5):985-1000.e6. doi: 10.1016/j.molcel.2019.01.004. Epub 2019 Jan 30.
Mol Cell. 2019.
PMID: 30711375
Free PMC article.
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