Nandakumar J - Search Results

1

TPP1 mutagenesis screens unravel shelterin interfaces and functions in hematopoiesis.

Grill S, Padmanaban S, Friedman A, Perkey E, Allen F, Tesmer VM, Chase J, Khoriaty R, Keegan CE, Maillard I, Nandakumar J. Grill S, et al. Among authors: nandakumar j. JCI Insight. 2021 May 10;6(9):e138059. doi: 10.1172/jci.insight.138059. JCI Insight. 2021. PMID: 33822766 Free PMC article.

2

Hoyeraal-Hreidarsson syndrome caused by a germline mutation in the TEL patch of the telomere protein TPP1.

Kocak H, Ballew BJ, Bisht K, Eggebeen R, Hicks BD, Suman S, O'Neil A, Giri N; NCI DCEG Cancer Genomics Research Laboratory; NCI DCEG Cancer Sequencing Working Group; Maillard I, Alter BP, Keegan CE, Nandakumar J, Savage SA. Kocak H, et al. Among authors: nandakumar j. Genes Dev. 2014 Oct 1;28(19):2090-102. doi: 10.1101/gad.248567.114. Epub 2014 Sep 18. Genes Dev. 2014. PMID: 25233904 Free PMC article.

3

The shelterin complex and hematopoiesis.

Jones M, Bisht K, Savage SA, Nandakumar J, Keegan CE, Maillard I. Jones M, et al. Among authors: nandakumar j. J Clin Invest. 2016 May 2;126(5):1621-9. doi: 10.1172/JCI84547. Epub 2016 May 2. J Clin Invest. 2016. PMID: 27135879 Free PMC article. Review.

4

Structural and functional consequences of a disease mutation in the telomere protein TPP1.

Bisht K, Smith EM, Tesmer VM, Nandakumar J. Bisht K, et al. Among authors: nandakumar j. Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13021-13026. doi: 10.1073/pnas.1605685113. Epub 2016 Nov 2. Proc Natl Acad Sci U S A. 2016. PMID: 27807141 Free PMC article.

5

A lentivirus-free inducible CRISPR-Cas9 system for efficient targeting of human genes.

Bisht K, Grill S, Graniel J, Nandakumar J. Bisht K, et al. Among authors: nandakumar j. Anal Biochem. 2017 Aug 1;530:40-49. doi: 10.1016/j.ab.2017.05.001. Epub 2017 May 4. Anal Biochem. 2017. PMID: 28477963 Free PMC article.

6

Dissecting the telomere-inner nuclear membrane interface formed in meiosis.

Pendlebury DF, Fujiwara Y, Tesmer VM, Smith EM, Shibuya H, Watanabe Y, Nandakumar J. Pendlebury DF, et al. Among authors: nandakumar j. Nat Struct Mol Biol. 2017 Dec;24(12):1064-1072. doi: 10.1038/nsmb.3493. Epub 2017 Oct 30. Nat Struct Mol Biol. 2017. PMID: 29083414 Free PMC article.

7

The N Terminus of the OB Domain of Telomere Protein TPP1 Is Critical for Telomerase Action.

Grill S, Tesmer VM, Nandakumar J. Grill S, et al. Among authors: nandakumar j. Cell Rep. 2018 Jan 30;22(5):1132-1140. doi: 10.1016/j.celrep.2018.01.012. Cell Rep. 2018. PMID: 29386102 Free PMC article.

8

Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells.

Grill S, Bisht K, Tesmer VM, Shami AN, Hammoud SS, Nandakumar J. Grill S, et al. Among authors: nandakumar j. Cell Rep. 2019 Jun 18;27(12):3511-3521.e7. doi: 10.1016/j.celrep.2019.05.073. Cell Rep. 2019. PMID: 31216472 Free PMC article.

9

Structural biology of telomeres and telomerase.

Smith EM, Pendlebury DF, Nandakumar J. Smith EM, et al. Among authors: nandakumar j. Cell Mol Life Sci. 2020 Jan;77(1):61-79. doi: 10.1007/s00018-019-03369-x. Epub 2019 Nov 14. Cell Mol Life Sci. 2020. PMID: 31728577 Free PMC article. Review.

10

Combining conservation and species-specific differences to determine how human telomerase binds telomeres.

Tesmer VM, Smith EM, Danciu O, Padmanaban S, Nandakumar J. Tesmer VM, et al. Among authors: nandakumar j. Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26505-26515. doi: 10.1073/pnas.1911912116. Epub 2019 Dec 10. Proc Natl Acad Sci U S A. 2019. PMID: 31822618 Free PMC article.

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