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SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.
Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman JE, Tromp G, Fuchsberger C, Gorski M, Lyytikäinen LP, Nutile T, Sedaghat S, Sorice R, Tin A, Yang Q, Ahluwalia TS, Arking DE, Bihlmeyer NA, Böger CA, Carroll RJ, Chasman DI, Cornelis MC, Dehghan A, Faul JD, Feitosa MF, Gambaro G, Gasparini P, Giulianini F, Heid I, Huang J, Imboden M, Jackson AU, Jeff J, Jhun MA, Katz R, Kifley A, Kilpeläinen TO, Kumar A, Laakso M, Li-Gao R, Lohman K, Lu Y, Mägi R, Malerba G, Mihailov E, Mohlke KL, Mook-Kanamori DO, Robino A, Ruderfer D, Salvi E, Schick UM, Schulz CA, Smith AV, Smith JA, Traglia M, Yerges-Armstrong LM, Zhao W, Goodarzi MO, Kraja AT, Liu C, Wessel J; CHARGE Glycemic-T2D Working Group,; CHARGE Blood Pressure Working Group,; Boerwinkle E, Borecki IB, Bork-Jensen J, Bottinger EP, Braga D, Brandslund I, Brody JA, Campbell A, Carey DJ, Christensen C, Coresh J, Crook E, Curhan GC, Cusi D, de Boer IH, de Vries AP, Denny JC, Devuyst O, Dreisbach AW, Endlich K, Esko T, Franco OH, Fulop T, Gerhard GS, Glümer C, Gottesman O, Grarup N, Gudnason V, Hansen T, Harris TB, Hayward C, Hocking L, Hofman A, Hu FB, Husemoen LL, Jackson RD, Jørgensen T, Jørgensen ME, Kähönen M, Kardia SL, König W, Koope… See abstract for full author list ➔ Li M, et al. J Am Soc Nephrol. 2017 Mar;28(3):981-994. doi: 10.1681/ASN.2016020131. Epub 2016 Dec 5. J Am Soc Nephrol. 2017. PMID: 27920155 Free PMC article.
The role of machine learning in clinical research: transforming the future of evidence generation.
Weissler EH, Naumann T, Andersson T, Ranganath R, Elemento O, Luo Y, Freitag DF, Benoit J, Hughes MC, Khan F, Slater P, Shameer K, Roe M, Hutchison E, Kollins SH, Broedl U, Meng Z, Wong JL, Curtis L, Huang E, Ghassemi M. Weissler EH, et al. Among authors: freitag df. Trials. 2021 Aug 16;22(1):537. doi: 10.1186/s13063-021-05489-x. Trials. 2021. PMID: 34399832 Free PMC article. Review.
Author Correction: Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism.
Cheng Y, Schlosser P, Hertel J, Sekula P, Oefner PJ, Spiekerkoetter U, Mielke J, Freitag DF, Schmidts M; GCKD Investigators; Kronenberg F, Eckardt KU, Thiele I, Li Y, Köttgen A. Cheng Y, et al. Among authors: freitag df. Nat Commun. 2021 Oct 6;12(1):5938. doi: 10.1038/s41467-021-26242-7. Nat Commun. 2021. PMID: 34615878 Free PMC article. No abstract available.
Genetic and environmental determinants of diastolic heart function.
Thanaj M, Mielke J, McGurk KA, Bai W, Savioli N, de Marvao A, Meyer HV, Zeng L, Sohler F, Lumbers RT, Wilkins MR, Ware JS, Bender C, Rueckert D, MacNamara A, Freitag DF, O'Regan DP. Thanaj M, et al. Among authors: freitag df. Nat Cardiovasc Res. 2022 Apr;1(4):361-371. doi: 10.1038/s44161-022-00048-2. Epub 2022 Apr 13. Nat Cardiovasc Res. 2022. PMID: 35479509 Free PMC article.
Environmental and genetic predictors of human cardiovascular ageing.
Shah M, de A Inácio MH, Lu C, Schiratti PR, Zheng SL, Clement A, de Marvao A, Bai W, King AP, Ware JS, Wilkins MR, Mielke J, Elci E, Kryukov I, McGurk KA, Bender C, Freitag DF, O'Regan DP. Shah M, et al. Among authors: freitag df. Nat Commun. 2023 Aug 21;14(1):4941. doi: 10.1038/s41467-023-40566-6. Nat Commun. 2023. PMID: 37604819 Free PMC article.
Proteomic signatures improve risk prediction for common and rare diseases.
Carrasco-Zanini J, Pietzner M, Davitte J, Surendran P, Croteau-Chonka DC, Robins C, Torralbo A, Tomlinson C, Grünschläger F, Fitzpatrick N, Ytsma C, Kanno T, Gade S, Freitag D, Ziebell F, Haas S, Denaxas S, Betts JC, Wareham NJ, Hemingway H, Scott RA, Langenberg C. Carrasco-Zanini J, et al. Nat Med. 2024 Sep;30(9):2489-2498. doi: 10.1038/s41591-024-03142-z. Epub 2024 Jul 22. Nat Med. 2024. PMID: 39039249 Free PMC article.
Prevalence, phenotypic characteristics and prognostic role of apparent treatment resistant hypertension in the German Chronic Kidney Disease (GCKD) study.
Mielke J, Trucks-Jansen H, Schurmann C, Kotsis F, Köttgen A, Schneider MP, Eckardt KU; GCKD Investigators; Freitag DF, Eitner F, Becker MS. Mielke J, et al. Among authors: freitag df. J Hum Hypertens. 2023 May;37(5):345-353. doi: 10.1038/s41371-022-00701-0. Epub 2022 May 9. J Hum Hypertens. 2023. PMID: 35534618
42 results