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Page 1
TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL.
Malik-Chaudhry HK, Prabhakar K, Ugamraj HS, Boudreau AA, Buelow B, Dang K, Davison LM, Harris KE, Jorgensen B, Ogana H, Pham D, Schellenberger U, Van Schooten W, Buelow R, Iyer S, Trinklein ND, Rangaswamy US. Malik-Chaudhry HK, et al. Among authors: schellenberger u. MAbs. 2021 Jan-Dec;13(1):1890411. doi: 10.1080/19420862.2021.1890411. MAbs. 2021. PMID: 33818299 Free PMC article.
Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies.
Trinklein ND, Pham D, Schellenberger U, Buelow B, Boudreau A, Choudhry P, Clarke SC, Dang K, Harris KE, Iyer S, Jorgensen B, Pratap PP, Rangaswamy US, Ugamraj HS, Vafa O, Wiita AP, van Schooten W, Buelow R, Force Aldred S. Trinklein ND, et al. Among authors: schellenberger u. MAbs. 2019 May/Jun;11(4):639-652. doi: 10.1080/19420862.2019.1574521. Epub 2019 Feb 20. MAbs. 2019. PMID: 30698484 Free PMC article.
A T-cell engaging bispecific antibody with a tumor-selective bivalent folate receptor alpha binding arm for the treatment of ovarian cancer.
Avanzino BC, Prabhakar K, Dalvi P, Hartstein S, Kehm H, Balasubramani A, Boudreau AA, Buelow B, Chang K, Davison LM, Iyer S, Kalwit V, Lewis Wilson K, Malik-Chaudhry HK, Pierson W, Pineda G, Rangaswamy US, Saiganesh S, Schellenberger U, Ugamraj HS, Yabut RD, Buelow R, Chapman J, Trinklein ND, Harris KE. Avanzino BC, et al. Among authors: schellenberger u. Oncoimmunology. 2022 Aug 20;11(1):2113697. doi: 10.1080/2162402X.2022.2113697. eCollection 2022. Oncoimmunology. 2022. PMID: 36016696 Free PMC article.
A bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo expansion of CD8 and NK cells.
Harris KE, Lorentsen KJ, Malik-Chaudhry HK, Loughlin K, Basappa HM, Hartstein S, Ahmil G, Allen NS, Avanzino BC, Balasubramani A, Boudreau AA, Chang K, Cuturi MC, Davison LM, Ho DM, Iyer S, Rangaswamy US, Sankaran P, Schellenberger U, Buelow R, Trinklein ND. Harris KE, et al. Among authors: schellenberger u. Sci Rep. 2021 May 19;11(1):10592. doi: 10.1038/s41598-021-90096-8. Sci Rep. 2021. PMID: 34011961 Free PMC article.
Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release.
Dang K, Castello G, Clarke SC, Li Y, Balasubramani A, Boudreau A, Davison L, Harris KE, Pham D, Sankaran P, Ugamraj HS, Deng R, Kwek S, Starzinski A, Iyer S, van Schooten W, Schellenberger U, Sun W, Trinklein ND, Buelow R, Buelow B, Fong L, Dalvi P. Dang K, et al. Among authors: schellenberger u. J Immunother Cancer. 2021 Jun;9(6):e002488. doi: 10.1136/jitc-2021-002488. J Immunother Cancer. 2021. PMID: 34088740 Free PMC article.
TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity.
Ugamraj HS, Dang K, Ouisse LH, Buelow B, Chini EN, Castello G, Allison J, Clarke SC, Davison LM, Buelow R, Deng R, Iyer S, Schellenberger U, Manika SN, Bijpuria S, Musnier A, Poupon A, Cuturi MC, van Schooten W, Dalvi P. Ugamraj HS, et al. Among authors: schellenberger u. MAbs. 2022 Jan-Dec;14(1):2095949. doi: 10.1080/19420862.2022.2095949. MAbs. 2022. PMID: 35867844 Free PMC article.
Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies.
Harris KE, Aldred SF, Davison LM, Ogana HAN, Boudreau A, Brüggemann M, Osborn M, Ma B, Buelow B, Clarke SC, Dang KH, Iyer S, Jorgensen B, Pham DT, Pratap PP, Rangaswamy US, Schellenberger U, van Schooten WC, Ugamraj HS, Vafa O, Buelow R, Trinklein ND. Harris KE, et al. Among authors: schellenberger u. Front Immunol. 2018 Apr 24;9:889. doi: 10.3389/fimmu.2018.00889. eCollection 2018. Front Immunol. 2018. PMID: 29740455 Free PMC article.
Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies.
Clarke SC, Ma B, Trinklein ND, Schellenberger U, Osborn MJ, Ouisse LH, Boudreau A, Davison LM, Harris KE, Ugamraj HS, Balasubramani A, Dang KH, Jorgensen B, Ogana HAN, Pham DT, Pratap PP, Sankaran P, Anegon I, van Schooten WC, Brüggemann M, Buelow R, Force Aldred S. Clarke SC, et al. Among authors: schellenberger u. Front Immunol. 2019 Jan 7;9:3037. doi: 10.3389/fimmu.2018.03037. eCollection 2018. Front Immunol. 2019. PMID: 30666250 Free PMC article.
A selective insecticidal protein from Pseudomonas mosselii for corn rootworm control.
Wei JZ, O'Rear J, Schellenberger U, Rosen BA, Park YJ, McDonald MJ, Zhu G, Xie W, Kassa A, Procyk L, Perez Ortega C, Zhao JZ, Yalpani N, Crane VC, Diehn SH, Sandahl GA, Nelson ME, Lu AL, Wu G, Liu L. Wei JZ, et al. Among authors: schellenberger u. Plant Biotechnol J. 2018 Feb;16(2):649-659. doi: 10.1111/pbi.12806. Epub 2017 Oct 1. Plant Biotechnol J. 2018. PMID: 28796437 Free PMC article.
A selective insecticidal protein from Pseudomonas for controlling corn rootworms.
Schellenberger U, Oral J, Rosen BA, Wei JZ, Zhu G, Xie W, McDonald MJ, Cerf DC, Diehn SH, Crane VC, Sandahl GA, Zhao JZ, Nowatzki TM, Sethi A, Liu L, Pan Z, Wang Y, Lu AL, Wu G, Liu L. Schellenberger U, et al. Science. 2016 Nov 4;354(6312):634-637. doi: 10.1126/science.aaf6056. Epub 2016 Sep 22. Science. 2016. PMID: 27708055
34 results