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Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis.
Wiley CD, Sharma R, Davis SS, Lopez-Dominguez JA, Mitchell KP, Wiley S, Alimirah F, Kim DE, Payne T, Rosko A, Aimontche E, Deshpande SM, Neri F, Kuehnemann C, Demaria M, Ramanathan A, Campisi J. Wiley CD, et al. Among authors: mitchell kp. Cell Metab. 2021 Jun 1;33(6):1124-1136.e5. doi: 10.1016/j.cmet.2021.03.008. Epub 2021 Apr 2. Cell Metab. 2021. PMID: 33811820 Free PMC article.
A novel AhR ligand, 2AI, protects the retina from environmental stress.
Gutierrez MA, Davis SS, Rosko A, Nguyen SM, Mitchell KP, Mateen S, Neves J, Garcia TY, Mooney S, Perdew GH, Hubbard TD, Lamba DA, Ramanathan A. Gutierrez MA, et al. Among authors: mitchell kp. Sci Rep. 2016 Jul 1;6:29025. doi: 10.1038/srep29025. Sci Rep. 2016. PMID: 27364765 Free PMC article.