Koshikawa N - Search Results

1

A PI polyamide-TPP conjugate targeting a mtDNA mutation induces cell death of cancer cells with the mutation.

Koshikawa N, Yasui N, Kida Y, Shinozaki Y, Tsuji K, Watanabe T, Takenaga K, Nagase H. Koshikawa N, et al. Cancer Sci. 2021 Jun;112(6):2504-2512. doi: 10.1111/cas.14912. Epub 2021 May 2. Cancer Sci. 2021. PMID: 33811417 Free PMC article.

2

Hypoxic induction of hypoxia-inducible factor-1alpha and oxygen-regulated gene expression in mitochondrial DNA-depleted HeLa cells.

Enomoto N, Koshikawa N, Gassmann M, Hayashi J, Takenaga K. Enomoto N, et al. Among authors: koshikawa n. Biochem Biophys Res Commun. 2002 Sep 20;297(2):346-52. doi: 10.1016/s0006-291x(02)02186-1. Biochem Biophys Res Commun. 2002. PMID: 12237125

3

Inhibition of metastatic brain tumor growth by intramuscular administration of the endostatin gene.

Oga M, Takenaga K, Sato Y, Nakajima H, Koshikawa N, Osato K, Sakiyama S. Oga M, et al. Among authors: koshikawa n. Int J Oncol. 2003 Jul;23(1):73-9. Int J Oncol. 2003. PMID: 12792778

4

Constitutive upregulation of hypoxia-inducible factor-1alpha mRNA occurring in highly metastatic lung carcinoma cells leads to vascular endothelial growth factor overexpression upon hypoxic exposure.

Koshikawa N, Iyozumi A, Gassmann M, Takenaga K. Koshikawa N, et al. Oncogene. 2003 Oct 2;22(43):6717-24. doi: 10.1038/sj.onc.1206765. Oncogene. 2003. PMID: 14555985

5

Hypoxia-regulated expression of attenuated diphtheria toxin A fused with hypoxia-inducible factor-1alpha oxygen-dependent degradation domain preferentially induces apoptosis of hypoxic cells in solid tumor.

Koshikawa N, Takenaga K. Koshikawa N, et al. Cancer Res. 2005 Dec 15;65(24):11622-30. doi: 10.1158/0008-5472.CAN-05-0111. Cancer Res. 2005. PMID: 16357173

6

Hypoxia-inducible factor-1 mediates the expression of DNA polymerase iota in human tumor cells.

Ito A, Koshikawa N, Mochizuki S, Omura K, Takenaga K. Ito A, et al. Among authors: koshikawa n. Biochem Biophys Res Commun. 2006 Dec 8;351(1):306-11. doi: 10.1016/j.bbrc.2006.10.048. Epub 2006 Oct 16. Biochem Biophys Res Commun. 2006. PMID: 17056006

7

3-Methyladenine suppresses cell migration and invasion of HT1080 fibrosarcoma cells through inhibiting phosphoinositide 3-kinases independently of autophagy inhibition.

Ito S, Koshikawa N, Mochizuki S, Takenaga K. Ito S, et al. Among authors: koshikawa n. Int J Oncol. 2007 Aug;31(2):261-8. Int J Oncol. 2007. PMID: 17611681

8

ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis.

Ishikawa K, Takenaga K, Akimoto M, Koshikawa N, Yamaguchi A, Imanishi H, Nakada K, Honma Y, Hayashi J. Ishikawa K, et al. Among authors: koshikawa n. Science. 2008 May 2;320(5876):661-4. doi: 10.1126/science.1156906. Epub 2008 Apr 3. Science. 2008. PMID: 18388260 Free article.

9

Reversible regulation of metastasis by ROS-generating mtDNA mutations.

Ishikawa K, Koshikawa N, Takenaga K, Nakada K, Hayashi J. Ishikawa K, et al. Among authors: koshikawa n. Mitochondrion. 2008 Sep;8(4):339-44. doi: 10.1016/j.mito.2008.07.006. Epub 2008 Aug 8. Mitochondrion. 2008. PMID: 18727959 Review.

10

Enhanced glycolysis induced by mtDNA mutations does not regulate metastasis.

Ishikawa K, Hashizume O, Koshikawa N, Fukuda S, Nakada K, Takenaga K, Hayashi J. Ishikawa K, et al. Among authors: koshikawa n. FEBS Lett. 2008 Oct 15;582(23-24):3525-30. doi: 10.1016/j.febslet.2008.09.024. Epub 2008 Sep 19. FEBS Lett. 2008. PMID: 18805414 Free article.

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