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Covalent Cysteine Targeting of Bruton's Tyrosine Kinase (BTK) Family by Withaferin-A Reduces Survival of Glucocorticoid-Resistant Multiple Myeloma MM1 Cells.
Logie E, Chirumamilla CS, Perez-Novo C, Shaw P, Declerck K, Palagani A, Rangarajan S, Cuypers B, De Neuter N, Mobashar Hussain Urf Turabe F, Kumar Verma N, Bogaerts A, Laukens K, Offner F, Van Vlierberghe P, Van Ostade X, Berghe WV. Logie E, et al. Among authors: van ostade x, van vlierberghe p. Cancers (Basel). 2021 Mar 31;13(7):1618. doi: 10.3390/cancers13071618. Cancers (Basel). 2021. PMID: 33807411 Free PMC article.
Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF.
Liang KL, Roels J, Lavaert M, Putteman T, Boehme L, Tilleman L, Velghe I, Pegoretti V, Van de Walle I, Sontag S, Vandewalle J, Vandekerckhove B, Leclercq G, Van Vlierberghe P, Libert C, Van Nieuwerburgh F, Fischer R, Kontermann RE, Pfizenmaier K, Doody G, Zenke M, Taghon T. Liang KL, et al. Among authors: van de walle i, van nieuwerburgh f, van vlierberghe p. Nat Immunol. 2023 Mar;24(3):474-486. doi: 10.1038/s41590-022-01417-6. Epub 2023 Jan 26. Nat Immunol. 2023. PMID: 36703005 Free article.
RNA helicase DHX15 exemplifies a unique dependency in acute leukemia.
Guo H, Xu J, Xing P, Li Q, Wang D, Tang C, Palhais B, Roels J, Liu J, Pan S, Huang J, Liu Z, Zhu P, Taghon T, Qing G, Van Vlierberghe P, Liu H. Guo H, et al. Among authors: van vlierberghe p. Haematologica. 2023 Aug 1;108(8):2029-2043. doi: 10.3324/haematol.2022.282066. Haematologica. 2023. PMID: 36861414 Free PMC article.
BCAT1 is a NOTCH1 target and sustains the oncogenic function of NOTCH1.
Tosello V, Di Martino L, Papathanassiu AE, Santa SD, Pizzi M, Mussolin L, Liu J, Van Vlierberghe P, Piovan E. Tosello V, et al. Among authors: van vlierberghe p. Haematologica. 2024 Sep 5. doi: 10.3324/haematol.2024.285552. Online ahead of print. Haematologica. 2024. PMID: 39234857 Free article.
Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia.
Roels J, Thénoz M, Szarzyńska B, Landfors M, De Coninck S, Demoen L, Provez L, Kuchmiy A, Strubbe S, Reunes L, Pieters T, Matthijssens F, Van Loocke W, Erarslan-Uysal B, Richter-Pechańska P, Declerck K, Lammens T, De Moerloose B, Deforce D, Van Nieuwerburgh F, Cheung LC, Kotecha RS, Mansour MR, Ghesquière B, Van Camp G, Berghe WV, Kowalczyk JR, Szczepański T, Davé UP, Kulozik AE, Goossens S, Curtis DJ, Taghon T, Dawidowska M, Degerman S, Van Vlierberghe P. Roels J, et al. Among authors: van nieuwerburgh f, van loocke w, van vlierberghe p, van camp g. Blood Cancer Discov. 2020 Nov;1(3):274-289. doi: 10.1158/2643-3230.BCD-20-0059. Epub 2020 Sep 23. Blood Cancer Discov. 2020. PMID: 33179015 Free PMC article.
Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice.
Pieters T, T'Sas S, Vanhee S, Almeida A, Driege Y, Roels J, Van Loocke W, Daneels W, Baens M, Marchand A, Van Trimpont M, Matthijssens F, Morscio J, Lemeire K, Lintermans B, Reunes L, Chaltin P, Offner F, Van Dorpe J, Hochepied T, Berx G, Beyaert R, Staal J, Van Vlierberghe P, Goossens S. Pieters T, et al. Among authors: van dorpe j, van trimpont m, van loocke w, van vlierberghe p. J Exp Med. 2021 Oct 4;218(10):e20202280. doi: 10.1084/jem.20202280. Epub 2021 Aug 18. J Exp Med. 2021. PMID: 34406363 Free PMC article.
Novel Insights on the Use of L-Asparaginase as an Efficient and Safe Anti-Cancer Therapy.
Van Trimpont M, Peeters E, De Visser Y, Schalk AM, Mondelaers V, De Moerloose B, Lavie A, Lammens T, Goossens S, Van Vlierberghe P. Van Trimpont M, et al. Among authors: van vlierberghe p. Cancers (Basel). 2022 Feb 11;14(4):902. doi: 10.3390/cancers14040902. Cancers (Basel). 2022. PMID: 35205650 Free PMC article. Review.
Engraftment of Allotransplanted Tumor Cells in Adult rag2 Mutant Xenopus tropicalis.
Tulkens D, Dimitrakopoulou D, Boelens M, Van Nieuwenhuysen T, Demuynck S, Toussaint W, Creytens D, Van Vlierberghe P, Vleminckx K. Tulkens D, et al. Among authors: van nieuwenhuysen t, van vlierberghe p. Cancers (Basel). 2022 Sep 20;14(19):4560. doi: 10.3390/cancers14194560. Cancers (Basel). 2022. PMID: 36230482 Free PMC article.
149 results