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Patient-Reported Symptoms and Disease Impacts in Adults With Moderate-to-Severe Atopic Dermatitis: Results From a Phase 2b Study With Abrocitinib.
Simpson EL, Wollenberg A, Bissonnette R, Silverberg JI, Papacharalambous J, Zhu L, Zhang W, Beebe JS, Vincent M, Peeva E, Bushmakin AG, Cappelleri JC, Chen L, Sikirica V, Xenakis J. Simpson EL, et al. Among authors: zhu l. Dermatitis. 2021 Oct 1;32(1S):S53-S61. doi: 10.1097/DER.0000000000000725. Dermatitis. 2021. PMID: 33795561 Clinical Trial.
A phase 2a randomized, placebo-controlled study to evaluate the efficacy and safety of the oral Janus kinase inhibitors ritlecitinib and brepocitinib in alopecia areata: 24-week results.
King B, Guttman-Yassky E, Peeva E, Banerjee A, Sinclair R, Pavel AB, Zhu L, Cox LA, Craiglow B, Chen L, Banfield C, Page K, Zhang W, Vincent MS. King B, et al. Among authors: zhu l. J Am Acad Dermatol. 2021 Aug;85(2):379-387. doi: 10.1016/j.jaad.2021.03.050. Epub 2021 Mar 20. J Am Acad Dermatol. 2021. PMID: 33757798 Free article. Clinical Trial.
Ritlecitinib and brepocitinib demonstrate significant improvement in scalp alopecia areata biomarkers.
Guttman-Yassky E, Pavel AB, Diaz A, Zhang N, Del Duca E, Estrada Y, King B, Banerjee A, Banfield C, Cox LA, Dowty ME, Page K, Vincent MS, Zhang W, Zhu L, Peeva E. Guttman-Yassky E, et al. Among authors: zhu l. J Allergy Clin Immunol. 2022 Apr;149(4):1318-1328. doi: 10.1016/j.jaci.2021.10.036. Epub 2021 Dec 1. J Allergy Clin Immunol. 2022. PMID: 34863853 Free article. Clinical Trial.
Maintenance, withdrawal, and re-treatment with ritlecitinib and brepocitinib in patients with alopecia areata in a single-blind extension of a phase 2a randomized clinical trial.
Peeva E, Guttman-Yassky E, Banerjee A, Sinclair R, Cox LA, Zhu L, Zhu H, Vincent M, King B. Peeva E, et al. Among authors: zhu h, zhu l. J Am Acad Dermatol. 2022 Aug;87(2):390-393. doi: 10.1016/j.jaad.2021.12.008. Epub 2021 Dec 13. J Am Acad Dermatol. 2022. PMID: 34915057 Free article. Clinical Trial. No abstract available.
2024 White paper on recent issues in bioanalysis: Impact of LDT in US and IVDR in EU; AI/ML for High Parameter Flow Cytometry; The rise of Olink Technology; CDx for AAV Gene Therapies; Integrative Bioanalysis by Multiple Platforms; Super Sensitive ADA/NAb LBA (PART 2A - Recommendations on Advanced Strategies for Biomarkers, IVD/CDx Assays (BAV), Cell Based Assays (CBA), and Ligand-Binding Assays (LBA) PART 2B - Regulatory Agencies' Input on Biomarkers, IVD/CDx, and Biomarker Assay Validation).
Bivi N, Graham D, Joglekar L, McGuire K, Stoop J, Zoghbi J, Baker B, Bandukwala A, Bond S, Buoninfante A, Chen J, Dysinger M, Engelbergs J, Fiscella M, Garofolo F, Hopper S, Jones B, King L, Murphy R, Palmer R, Sanderink G, Seyda A, Tang H, Van Tuyl A, Wagner L, Walravens K, Wang K, Zander H, Zhu L, Li M, Lin YD, Natalia M, Standifer N, Eck S, Goihberg P, Grugan K, Hedrick MN, Hopkins G, Kar S, Keller S, McGrath S, O'Gorman B, Stevens C, Stevens E, Terszowski G, Trampont PC, Yao S, Joyce A, Kumar S, Owen C, Pine S, Yearwood G, Cao L, Clausen V, Coble K, Culbert A, Gupta S, Hughes R, Liu S, Lu K, Martello R, Reese KJ, Stubenrauch KG, Wen Y. Bivi N, et al. Among authors: zhu l. Bioanalysis. 2025 Jan 25:1-38. doi: 10.1080/17576180.2024.2442218. Online ahead of print. Bioanalysis. 2025. PMID: 39862107
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