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Page 1
Designed proteins assemble antibodies into modular nanocages.
Divine R, Dang HV, Ueda G, Fallas JA, Vulovic I, Sheffler W, Saini S, Zhao YT, Raj IX, Morawski PA, Jennewein MF, Homad LJ, Wan YH, Tooley MR, Seeger F, Etemadi A, Fahning ML, Lazarovits J, Roederer A, Walls AC, Stewart L, Mazloomi M, King NP, Campbell DJ, McGuire AT, Stamatatos L, Ruohola-Baker H, Mathieu J, Veesler D, Baker D. Divine R, et al. Among authors: stewart l. Science. 2021 Apr 2;372(6537):eabd9994. doi: 10.1126/science.abd9994. Science. 2021. PMID: 33795432 Free PMC article.
A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response.
Koday MT, Nelson J, Chevalier A, Koday M, Kalinoski H, Stewart L, Carter L, Nieusma T, Lee PS, Ward AB, Wilson IA, Dagley A, Smee DF, Baker D, Fuller DH. Koday MT, et al. Among authors: stewart l. PLoS Pathog. 2016 Feb 4;12(2):e1005409. doi: 10.1371/journal.ppat.1005409. eCollection 2016 Feb. PLoS Pathog. 2016. PMID: 26845438 Free PMC article.
De novo design of self-assembling helical protein filaments.
Shen H, Fallas JA, Lynch E, Sheffler W, Parry B, Jannetty N, Decarreau J, Wagenbach M, Vicente JJ, Chen J, Wang L, Dowling Q, Oberdorfer G, Stewart L, Wordeman L, De Yoreo J, Jacobs-Wagner C, Kollman J, Baker D. Shen H, et al. Among authors: stewart l. Science. 2018 Nov 9;362(6415):705-709. doi: 10.1126/science.aau3775. Science. 2018. PMID: 30409885 Free PMC article.
Computational design of transmembrane pores.
Xu C, Lu P, Gamal El-Din TM, Pei XY, Johnson MC, Uyeda A, Bick MJ, Xu Q, Jiang D, Bai H, Reggiano G, Hsia Y, Brunette TJ, Dou J, Ma D, Lynch EM, Boyken SE, Huang PS, Stewart L, DiMaio F, Kollman JM, Luisi BF, Matsuura T, Catterall WA, Baker D. Xu C, et al. Among authors: stewart l. Nature. 2020 Sep;585(7823):129-134. doi: 10.1038/s41586-020-2646-5. Epub 2020 Aug 26. Nature. 2020. PMID: 32848250 Free PMC article.
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.
Cao L, Goreshnik I, Coventry B, Case JB, Miller L, Kozodoy L, Chen RE, Carter L, Walls AC, Park YJ, Strauch EM, Stewart L, Diamond MS, Veesler D, Baker D. Cao L, et al. Among authors: stewart l. Science. 2020 Oct 23;370(6515):426-431. doi: 10.1126/science.abd9909. Epub 2020 Sep 9. Science. 2020. PMID: 32907861 Free PMC article.
Designed proteins assemble antibodies into modular nanocages.
Divine R, Dang HV, Ueda G, Fallas JA, Vulovic I, Sheffler W, Saini S, Zhao YT, Raj IX, Morawski PA, Jennewein MF, Homad LJ, Wan YH, Tooley MR, Seeger F, Etemadi A, Fahning ML, Lazarovits J, Roederer A, Walls AC, Stewart L, Mazloomi M, King NP, Campbell DJ, McGuire AT, Stamatatos L, Ruohola-Baker H, Mathieu J, Veesler D, Baker D. Divine R, et al. Among authors: stewart l. bioRxiv [Preprint]. 2020 Dec 1:2020.12.01.406611. doi: 10.1101/2020.12.01.406611. bioRxiv. 2020. Update in: Science. 2021 Apr 2;372(6537):eabd9994. doi: 10.1126/science.abd9994 PMID: 33299994 Free PMC article. Updated. Preprint.
De novo design of modular and tunable protein biosensors.
Quijano-Rubio A, Yeh HW, Park J, Lee H, Langan RA, Boyken SE, Lajoie MJ, Cao L, Chow CM, Miranda MC, Wi J, Hong HJ, Stewart L, Oh BH, Baker D. Quijano-Rubio A, et al. Among authors: stewart l. Nature. 2021 Mar;591(7850):482-487. doi: 10.1038/s41586-021-03258-z. Epub 2021 Jan 27. Nature. 2021. PMID: 33503651 Free PMC article.
In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19.
Phan IQ, Subramanian S, Kim D, Murphy M, Pettie D, Carter L, Anishchenko I, Barrett LK, Craig J, Tillery L, Shek R, Harrington WE, Koelle DM, Wald A, Veesler D, King N, Boonyaratanakornkit J, Isoherranen N, Greninger AL, Jerome KR, Chu H, Staker B, Stewart L, Myler PJ, Van Voorhis WC. Phan IQ, et al. Among authors: stewart l. Sci Rep. 2021 Feb 22;11(1):4290. doi: 10.1038/s41598-021-83730-y. Sci Rep. 2021. PMID: 33619344 Free PMC article.
Quadrivalent influenza nanoparticle vaccines induce broad protection.
Boyoglu-Barnum S, Ellis D, Gillespie RA, Hutchinson GB, Park YJ, Moin SM, Acton OJ, Ravichandran R, Murphy M, Pettie D, Matheson N, Carter L, Creanga A, Watson MJ, Kephart S, Ataca S, Vaile JR, Ueda G, Crank MC, Stewart L, Lee KK, Guttman M, Baker D, Mascola JR, Veesler D, Graham BS, King NP, Kanekiyo M. Boyoglu-Barnum S, et al. Among authors: stewart l. Nature. 2021 Apr;592(7855):623-628. doi: 10.1038/s41586-021-03365-x. Epub 2021 Mar 24. Nature. 2021. PMID: 33762730 Free PMC article.
1,670 results