McGuire AT - Search Results

1

Designed proteins assemble antibodies into modular nanocages.

Divine R, Dang HV, Ueda G, Fallas JA, Vulovic I, Sheffler W, Saini S, Zhao YT, Raj IX, Morawski PA, Jennewein MF, Homad LJ, Wan YH, Tooley MR, Seeger F, Etemadi A, Fahning ML, Lazarovits J, Roederer A, Walls AC, Stewart L, Mazloomi M, King NP, Campbell DJ, McGuire AT, Stamatatos L, Ruohola-Baker H, Mathieu J, Veesler D, Baker D. Divine R, et al. Among authors: mcguire at. Science. 2021 Apr 2;372(6537):eabd9994. doi: 10.1126/science.abd9994. Science. 2021. PMID: 33795432 Free PMC article.

2

Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs.

Hoot S, McGuire AT, Cohen KW, Strong RK, Hangartner L, Klein F, Diskin R, Scheid JF, Sather DN, Burton DR, Stamatatos L. Hoot S, et al. Among authors: mcguire at. PLoS Pathog. 2013 Jan;9(1):e1003106. doi: 10.1371/journal.ppat.1003106. Epub 2013 Jan 3. PLoS Pathog. 2013. PMID: 23300456 Free PMC article.

3

Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies.

McGuire AT, Hoot S, Dreyer AM, Lippy A, Stuart A, Cohen KW, Jardine J, Menis S, Scheid JF, West AP, Schief WR, Stamatatos L. McGuire AT, et al. J Exp Med. 2013 Apr 8;210(4):655-63. doi: 10.1084/jem.20122824. Epub 2013 Mar 25. J Exp Med. 2013. PMID: 23530120 Free PMC article.

4

Rational HIV immunogen design to target specific germline B cell receptors.

Jardine J, Julien JP, Menis S, Ota T, Kalyuzhniy O, McGuire A, Sok D, Huang PS, MacPherson S, Jones M, Nieusma T, Mathison J, Baker D, Ward AB, Burton DR, Stamatatos L, Nemazee D, Wilson IA, Schief WR. Jardine J, et al. Science. 2013 May 10;340(6133):711-6. doi: 10.1126/science.1234150. Epub 2013 Mar 28. Science. 2013. PMID: 23539181 Free PMC article.

5

Diverse recombinant HIV-1 Envs fail to activate B cells expressing the germline B cell receptors of the broadly neutralizing anti-HIV-1 antibodies PG9 and 447-52D.

McGuire AT, Glenn JA, Lippy A, Stamatatos L. McGuire AT, et al. J Virol. 2014 Mar;88(5):2645-57. doi: 10.1128/JVI.03228-13. Epub 2013 Dec 18. J Virol. 2014. PMID: 24352455 Free PMC article.

6

HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies.

McGuire AT, Dreyer AM, Carbonetti S, Lippy A, Glenn J, Scheid JF, Mouquet H, Stamatatos L. McGuire AT, et al. Science. 2014 Dec 12;346(6215):1380-1383. doi: 10.1126/science.1259206. Science. 2014. PMID: 25504724 Free PMC article.

7

Correction for McGuire et al., diverse recombinant HIV-1 Envs fail to activate B cells expressing the germline B cell receptors of the broadly neutralizing anti-HIV-1 antibodies PG9 and 447-52D.

McGuire AT, Glenn JA, Lippy A, Stamatatos L. McGuire AT, et al. J Virol. 2015 May;89(9):5194. doi: 10.1128/JVI.00341-15. J Virol. 2015. PMID: 25841051 Free PMC article. No abstract available.

8

Common Characteristics of HIV-Neutralizing Antibodies with a Fondness for Sugars.

McGuire AT, Stamatatos L. McGuire AT, et al. Immunity. 2015 Nov 17;43(5):837-40. doi: 10.1016/j.immuni.2015.10.026. Immunity. 2015. PMID: 26588775 Free article.

9

Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice.

McGuire AT, Gray MD, Dosenovic P, Gitlin AD, Freund NT, Petersen J, Correnti C, Johnsen W, Kegel R, Stuart AB, Glenn J, Seaman MS, Schief WR, Strong RK, Nussenzweig MC, Stamatatos L. McGuire AT, et al. Nat Commun. 2016 Feb 24;7:10618. doi: 10.1038/ncomms10618. Nat Commun. 2016. PMID: 26907590 Free PMC article.

10

Structural basis for germline antibody recognition of HIV-1 immunogens.

Scharf L, West AP, Sievers SA, Chen C, Jiang S, Gao H, Gray MD, McGuire AT, Scheid JF, Nussenzweig MC, Stamatatos L, Bjorkman PJ. Scharf L, et al. Among authors: mcguire at. Elife. 2016 Mar 21;5:e13783. doi: 10.7554/eLife.13783. Elife. 2016. PMID: 26997349 Free PMC article.

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