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Page 1
Efficacy of a Broadly Neutralizing SARS-CoV-2 Ferritin Nanoparticle Vaccine in Nonhuman Primates.
Joyce MG, King HAD, Naouar IE, Ahmed A, Peachman KK, Cincotta CM, Subra C, Chen RE, Thomas PV, Chen WH, Sankhala RS, Hajduczki A, Martinez EJ, Peterson CE, Chang WC, Choe M, Smith C, Lee PJ, Headley JA, Taddese MG, Elyard HA, Cook A, Anderson A, McGuckin-Wuertz K, Dong M, Swafford I, Case JB, Currier JR, Lal KG, O'Connell RJ, Molnar S, Nair MS, Dussupt V, Daye SP, Zeng X, Barkei EK, Staples HM, Alfson K, Carrion R, Krebs SJ, Paquin-Proulx D, Karasavva N, Polonis VR, Jagodzinski LL, Amare MF, Vasan S, Scott PT, Huang Y, Ho DD, de Val N, Diamond MS, Lewis MG, Rao M, Matyas GR, Gromowski GD, Peel SA, Michael NL, Bolton DL, Modjarrad K. Joyce MG, et al. Among authors: case jb. bioRxiv [Preprint]. 2021 Mar 25:2021.03.24.436523. doi: 10.1101/2021.03.24.436523. bioRxiv. 2021. PMID: 33791694 Free PMC article. Preprint.
A public vaccine-induced human antibody protects against SARS-CoV-2 and emerging variants.
Schmitz AJ, Turner JS, Liu Z, Aziati ID, Chen RE, Joshi A, Bricker TL, Darling TL, Adelsberg DC, Alsoussi WB, Case JB, Lei T, Thapa M, Amanat F, O'Halloran JA, Shi PY, Presti RM, Krammer F, Bajic G, Whelan SPJ, Diamond MS, Boon ACM, Ellebedy AH. Schmitz AJ, et al. Among authors: case jb. bioRxiv [Preprint]. 2021 Mar 24:2021.03.24.436864. doi: 10.1101/2021.03.24.436864. bioRxiv. 2021. Update in: Immunity. 2021 Sep 14;54(9):2159-2166.e6. doi: 10.1016/j.immuni.2021.08.013 PMID: 33791696 Free PMC article. Updated. Preprint.
Assessment of serological assays for identifying high titer convalescent plasma.
Farnsworth CW, Case JB, Hock K, Chen RE, O'Halloran JA, Presti R, Goss CW, Rauseo AM, Ellebedy A, Theel ES, Diamond MS, Henderson JP. Farnsworth CW, et al. Among authors: case jb. medRxiv [Preprint]. 2021 Mar 28:2021.03.26.21254427. doi: 10.1101/2021.03.26.21254427. medRxiv. 2021. Update in: Transfusion. 2021 Sep;61(9):2658-2667. doi: 10.1111/trf.16580 PMID: 33791711 Free PMC article. Updated. Preprint.
Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques.
King HAD, Gordon Joyce M, Naouar IE, Ahmed A, Cincotta CM, Subra C, Peachman KK, Hack HH, Chen RE, Thomas PV, Chen WH, Sankhala RS, Hajduczki A, Martinez EJ, Peterson CE, Chang WC, Choe M, Smith C, Headley JA, Elyard HA, Cook A, Anderson A, Wuertz KM, Dong M, Swafford I, Case JB, Currier JR, Lal KG, Amare MF, Dussupt V, Molnar S, Daye SP, Zeng X, Barkei EK, Alfson K, Staples HM, Carrion R, Krebs SJ, Paquin-Proulx D, Karasavvas N, Polonis VR, Jagodzinski LL, Vasan S, Scott PT, Huang Y, Nair MS, Ho DD, de Val N, Diamond MS, Lewis MG, Rao M, Matyas GR, Gromowski GD, Peel SA, Michael NL, Modjarrad K, Bolton DL. King HAD, et al. Among authors: case jb. bioRxiv [Preprint]. 2021 Apr 10:2021.04.09.439166. doi: 10.1101/2021.04.09.439166. bioRxiv. 2021. Update in: Proc Natl Acad Sci U S A. 2021 Sep 21;118(38):e2106433118. doi: 10.1073/pnas.2106433118 PMID: 33851155 Free PMC article. Updated. Preprint.
A potently neutralizing anti-SARS-CoV-2 antibody inhibits variants of concern by binding a highly conserved epitope.
VanBlargan L, Adams L, Liu Z, Chen RE, Gilchuk P, Raju S, Smith B, Zhao H, Case JB, Winkler ES, Whitener B, Droit L, Aziati I, Shi PY, Creanga A, Pegu A, Handley S, Wang D, Boon A, Crowe JE, Whelan SPJ, Fremont D, Diamond M. VanBlargan L, et al. Among authors: case jb. bioRxiv [Preprint]. 2021 Apr 26:2021.04.26.441501. doi: 10.1101/2021.04.26.441501. bioRxiv. 2021. Update in: Immunity. 2021 Oct 12;54(10):2399-2416.e6. doi: 10.1016/j.immuni.2021.08.016 PMID: 33907753 Free PMC article. Updated. Preprint.
SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity.
Joyce MG, Chen WH, Sankhala RS, Hajduczki A, Thomas PV, Choe M, Chang W, Peterson CE, Martinez E, Morrison EB, Smith C, Ahmed A, Wieczorek L, Anderson A, Chen RE, Case JB, Li Y, Oertel T, Rosado L, Ganesh A, Whalen C, Carmen JM, Mendez-Rivera L, Karch C, Gohain N, Villar Z, McCurdy D, Beck Z, Kim J, Shrivastava S, Jobe O, Dussupt V, Molnar S, Tran U, Kannadka CB, Zemil M, Khanh H, Wu W, Cole MA, Duso DK, Kummer LW, Lang TJ, Muncil SE, Currier JR, Krebs SJ, Polonis VR, Rajan S, McTamney PM, Esser MT, Reiley WW, Rolland M, de Val N, Diamond MS, Gromowski GD, Matyas GR, Rao M, Michael NL, Modjarrad K. Joyce MG, et al. Among authors: case jb. bioRxiv [Preprint]. 2021 May 10:2021.05.09.443331. doi: 10.1101/2021.05.09.443331. bioRxiv. 2021. Update in: Cell Rep. 2021 Dec 21;37(12):110143. doi: 10.1016/j.celrep.2021.110143 PMID: 34013273 Free PMC article. Updated. Preprint.
Multivalent designed proteins protect against SARS-CoV-2 variants of concern.
Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vögeli B, Krüger-Gericke A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken S, Ljubetič A, Edman N, Ueda G, Chow C, Addetia A, Panpradist N, Gale M Jr, Freedman BS, Lutz BR, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D. Hunt AC, et al. Among authors: case jb. bioRxiv [Preprint]. 2021 Jul 7:2021.07.07.451375. doi: 10.1101/2021.07.07.451375. bioRxiv. 2021. Update in: Sci Transl Med. 2022 May 25;14(646):eabn1252. doi: 10.1126/scitranslmed.abn1252 PMID: 34268509 Free PMC article. Updated. Preprint.
Boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibody responses and protection against B.1.1.529 infection in mice.
Ying B, Scheaffer SM, Whitener B, Liang CY, Dmytrenko O, Mackin S, Wu K, Lee D, Avena LE, Chong Z, Case JB, Ma L, Kim T, Sein C, Woods A, Berrueta DM, Carfi A, Elbashir SM, Edwards DK, Thackray LB, Diamond MS. Ying B, et al. Among authors: case jb. bioRxiv [Preprint]. 2022 Feb 9:2022.02.07.479419. doi: 10.1101/2022.02.07.479419. bioRxiv. 2022. PMID: 35169795 Free PMC article. Preprint.
Potent and pan-neutralization of SARS-CoV-2 variants of concern by DARPins.
Chonira V, Kwon YD, Gorman J, Case JB, Ku Z, Simeon R, Casner RG, Harris DR, Olia AS, Stephens T, Shapiro L, Boyd H, Tsybovsky Y, Krammer F, Diamond MS, Kwong PD, An Z, Chen Z. Chonira V, et al. Among authors: case jb. bioRxiv [Preprint]. 2022 May 31:2022.05.30.493765. doi: 10.1101/2022.05.30.493765. bioRxiv. 2022. Update in: Nat Chem Biol. 2023 Mar;19(3):284-291. doi: 10.1038/s41589-022-01193-2 PMID: 35677079 Free PMC article. Updated. Preprint.
Computationally restoring the potency of a clinical antibody against SARS-CoV-2 Omicron subvariants.
Desautels TA, Arrildt KT, Zemla AT, Lau EY, Zhu F, Ricci D, Cronin S, Zost SJ, Binshtein E, Scheaffer SM, Dadonaite B, Petersen BK, Engdahl TB, Chen E, Handal LS, Hall L, Goforth JW, Vashchenko D, Nguyen S, Weilhammer DR, Lo JK, Rubinfeld B, Saada EA, Weisenberger T, Lee TH, Whitener B, Case JB, Ladd A, Silva MS, Haluska RM, Grzesiak EA, Earnhart CG, Hopkins S, Bates TW, Thackray LB, Segelke BW, Lillo AM, Sundaram S, Bloom J, Diamond MS, Crowe JE Jr, Carnahan RH, Faissol DM. Desautels TA, et al. Among authors: case jb. bioRxiv [Preprint]. 2023 Apr 24:2022.10.21.513237. doi: 10.1101/2022.10.21.513237. bioRxiv. 2023. Update in: Nature. 2024 May;629(8013):878-885. doi: 10.1038/s41586-024-07385-1 PMID: 36324800 Free PMC article. Updated. Preprint.
206 results