Hacker SM - Search Results

1

Broad Spectrum Antibiotic Xanthocillin X Effectively Kills Acinetobacter baumannii via Dysregulation of Heme Biosynthesis.

Hübner I, Shapiro JA, Hoßmann J, Drechsel J, Hacker SM, Rather PN, Pieper DH, Wuest WM, Sieber SA. Hübner I, et al. Among authors: hacker sm. ACS Cent Sci. 2021 Mar 24;7(3):488-498. doi: 10.1021/acscentsci.0c01621. Epub 2021 Jan 20. ACS Cent Sci. 2021. PMID: 33791430 Free PMC article.

2

Neocarzilin A Is a Potent Inhibitor of Cancer Cell Motility Targeting VAT-1 Controlled Pathways.

Gleissner CM, Pyka CL, Heydenreuter W, Gronauer TF, Atzberger C, Korotkov VS, Cheng W, Hacker SM, Vollmar AM, Braig S, Sieber SA. Gleissner CM, et al. Among authors: hacker sm. ACS Cent Sci. 2019 Jul 24;5(7):1170-1178. doi: 10.1021/acscentsci.9b00266. Epub 2019 Jun 18. ACS Cent Sci. 2019. PMID: 31403069 Free PMC article.

3

Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms.

Le P, Kunold E, Macsics R, Rox K, Jennings MC, Ugur I, Reinecke M, Chaves-Moreno D, Hackl MW, Fetzer C, Mandl FAM, Lehmann J, Korotkov VS, Hacker SM, Kuster B, Antes I, Pieper DH, Rohde M, Wuest WM, Medina E, Sieber SA. Le P, et al. Among authors: hacker sm. Nat Chem. 2020 Feb;12(2):145-158. doi: 10.1038/s41557-019-0378-7. Epub 2019 Dec 16. Nat Chem. 2020. PMID: 31844194 Free PMC article.

4

Degrasyn exhibits antibiotic activity against multi-resistant Staphylococcus aureus by modifying several essential cysteines.

Lee KM, Le P, Sieber SA, Hacker SM. Lee KM, et al. Among authors: hacker sm. Chem Commun (Camb). 2020 Mar 5;56(19):2929-2932. doi: 10.1039/c9cc09204h. Chem Commun (Camb). 2020. PMID: 32039420

5

Light-Activatable, 2,5-Disubstituted Tetrazoles for the Proteome-wide Profiling of Aspartates and Glutamates in Living Bacteria.

Bach K, Beerkens BLH, Zanon PRA, Hacker SM. Bach K, et al. Among authors: hacker sm. ACS Cent Sci. 2020 Apr 22;6(4):546-554. doi: 10.1021/acscentsci.9b01268. Epub 2020 Apr 13. ACS Cent Sci. 2020. PMID: 32342004 Free PMC article.

6

A tailored phosphoaspartate probe unravels CprR as a response regulator in Pseudomonas aeruginosa interkingdom signaling.

Allihn PWA, Hackl MW, Ludwig C, Hacker SM, Sieber SA. Allihn PWA, et al. Among authors: hacker sm. Chem Sci. 2021 Feb 8;12(13):4763-4770. doi: 10.1039/d0sc06226j. Chem Sci. 2021. PMID: 34168754 Free PMC article.

7

Eukaryotic catecholamine hormones influence the chemotactic control of Vibrio campbellii by binding to the coupling protein CheW.

Weigert Muñoz A, Hoyer E, Schumacher K, Grognot M, Taute KM, Hacker SM, Sieber SA, Jung K. Weigert Muñoz A, et al. Among authors: hacker sm. Proc Natl Acad Sci U S A. 2022 Mar 8;119(10):e2118227119. doi: 10.1073/pnas.2118227119. Epub 2022 Mar 1. Proc Natl Acad Sci U S A. 2022. PMID: 35238645 Free PMC article.

8

A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites.

Dienemann JN, Chen SY, Hitzenberger M, Sievert ML, Hacker SM, Prigge ST, Zacharias M, Groll M, Sieber SA. Dienemann JN, et al. Among authors: hacker sm. Angew Chem Int Ed Engl. 2023 Aug 1;62(31):e202304533. doi: 10.1002/anie.202304533. Epub 2023 Jun 26. Angew Chem Int Ed Engl. 2023. PMID: 37249408 Free PMC article.

9

A chemical probe unravels the reactive proteome of health-associated catechols.

Weigert Muñoz A, Meighen-Berger KM, Hacker SM, Feige MJ, Sieber SA. Weigert Muñoz A, et al. Among authors: hacker sm. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16. Chem Sci. 2023. PMID: 37592978 Free PMC article.

10

A proteome-wide atlas of lysine-reactive chemistry.

Abbasov ME, Kavanagh ME, Ichu TA, Lazear MR, Tao Y, Crowley VM, Am Ende CW, Hacker SM, Ho J, Dix MM, Suciu R, Hayward MM, Kiessling LL, Cravatt BF. Abbasov ME, et al. Among authors: hacker sm. Nat Chem. 2021 Nov;13(11):1081-1092. doi: 10.1038/s41557-021-00765-4. Epub 2021 Sep 9. Nat Chem. 2021. PMID: 34504315 Free PMC article.

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