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Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling.
Sandercock AM, Rust S, Guillard S, Sachsenmeier KF, Holoweckyj N, Hay C, Flynn M, Huang Q, Yan K, Herpers B, Price LS, Soden J, Freeth J, Jermutus L, Hollingsworth R, Minter R. Sandercock AM, et al. Among authors: herpers b. Mol Cancer. 2015 Jul 31;14:147. doi: 10.1186/s12943-015-0415-0. Mol Cancer. 2015. PMID: 26227951 Free PMC article.
The nuclear factor κB family member RelB facilitates apoptosis of renal epithelial cells caused by cisplatin/tumor necrosis factor α synergy by suppressing an epithelial to mesenchymal transition-like phenotypic switch.
Benedetti G, Fokkelman M, Yan K, Fredriksson L, Herpers B, Meerman J, van de Water B, de Graauw M. Benedetti G, et al. Among authors: herpers b. Mol Pharmacol. 2013 Jul;84(1):128-38. doi: 10.1124/mol.112.084053. Epub 2013 Apr 26. Mol Pharmacol. 2013. PMID: 23625948
3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors.
Badder LM, Hollins AJ, Herpers B, Yan K, Ewan KB, Thomas M, Shone JR, Badder DA, Naven M, Ashelford KE, Hargest R, Clarke AR, Esdar C, Buchstaller HP, Treherne JM, Boj S, Ramezanpour B, Wienke D, Price LS, Shaw PH, Dale TC. Badder LM, et al. Among authors: herpers b. PLoS One. 2020 Aug 18;15(8):e0235319. doi: 10.1371/journal.pone.0235319. eCollection 2020. PLoS One. 2020. PMID: 32810173 Free PMC article.
88 results