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A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target.
Srivastava PK, van Eyll J, Godard P, Mazzuferi M, Delahaye-Duriez A, Van Steenwinckel J, Gressens P, Danis B, Vandenplas C, Foerch P, Leclercq K, Mairet-Coello G, Cardenas A, Vanclef F, Laaniste L, Niespodziany I, Keaney J, Gasser J, Gillet G, Shkura K, Chong SA, Behmoaras J, Kadiu I, Petretto E, Kaminski RM, Johnson MR. Srivastava PK, et al. Among authors: behmoaras j. Nat Commun. 2018 Sep 3;9(1):3561. doi: 10.1038/s41467-018-06008-4. Nat Commun. 2018. PMID: 30177815 Free PMC article.
Longitudinal proteomic profiling of dialysis patients with COVID-19 reveals markers of severity and predictors of death.
Gisby J, Clarke CL, Medjeral-Thomas N, Malik TH, Papadaki A, Mortimer PM, Buang NB, Lewis S, Pereira M, Toulza F, Fagnano E, Mawhin MA, Dutton EE, Tapeng L, Richard AC, Kirk PD, Behmoaras J, Sandhu E, McAdoo SP, Prendecki MF, Pickering MC, Botto M, Willicombe M, Thomas DC, Peters JE. Gisby J, et al. Among authors: behmoaras j. Elife. 2021 Mar 11;10:e64827. doi: 10.7554/eLife.64827. Elife. 2021. PMID: 33704068 Free PMC article.
Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus.
Johnson MR, Behmoaras J, Bottolo L, Krishnan ML, Pernhorst K, Santoscoy PLM, Rossetti T, Speed D, Srivastava PK, Chadeau-Hyam M, Hajji N, Dabrowska A, Rotival M, Razzaghi B, Kovac S, Wanisch K, Grillo FW, Slaviero A, Langley SR, Shkura K, Roncon P, De T, Mattheisen M, Niehusmann P, O'Brien TJ, Petrovski S, von Lehe M, Hoffmann P, Eriksson J, Coffey AJ, Cichon S, Walker M, Simonato M, Danis B, Mazzuferi M, Foerch P, Schoch S, De Paola V, Kaminski RM, Cunliffe VT, Becker AJ, Petretto E. Johnson MR, et al. Among authors: behmoaras j. Nat Commun. 2015 Jan 23;6:6031. doi: 10.1038/ncomms7031. Nat Commun. 2015. PMID: 25615886 Free PMC article.
Cardiac glycosides are broad-spectrum senolytics.
Guerrero A, Herranz N, Sun B, Wagner V, Gallage S, Guiho R, Wolter K, Pombo J, Irvine EE, Innes AJ, Birch J, Glegola J, Manshaei S, Heide D, Dharmalingam G, Harbig J, Olona A, Behmoaras J, Dauch D, Uren AG, Zender L, Vernia S, Martínez-Barbera JP, Heikenwalder M, Withers DJ, Gil J. Guerrero A, et al. Among authors: behmoaras j. Nat Metab. 2019 Nov;1(11):1074-1088. doi: 10.1038/s42255-019-0122-z. Epub 2019 Oct 21. Nat Metab. 2019. PMID: 31799499 Free PMC article.
Use of Quantitative Real Time Polymerase Chain Reaction to Assess Gene Transcripts Associated With Antibody-Mediated Rejection of Kidney Transplants.
Dominy KM, Roufosse C, de Kort H, Willicombe M, Brookes P, Behmoaras JV, Petretto EG, Galliford J, Choi P, Taube D, Cook HT, Mclean AG. Dominy KM, et al. Among authors: behmoaras jv. Transplantation. 2015 Sep;99(9):1981-8. doi: 10.1097/TP.0000000000000621. Transplantation. 2015. PMID: 25675206 Free article.
60 results