DeLeeuw LW - Search Results

1

POT1 stability and binding measured by fluorescence thermal shift assays.

DeLeeuw LW, Monsen RC, Petrauskas V, Gray RD, Baranauskiene L, Matulis D, Trent JO, Chaires JB. DeLeeuw LW, et al. PLoS One. 2021 Mar 30;16(3):e0245675. doi: 10.1371/journal.pone.0245675. eCollection 2021. PLoS One. 2021. PMID: 33784306 Free PMC article.

2

Human POT1 unfolds G-quadruplexes by conformational selection.

Chaires JB, Gray RD, Dean WL, Monsen R, DeLeeuw LW, Stribinskis V, Trent JO. Chaires JB, et al. Among authors: deleeuw lw. Nucleic Acids Res. 2020 May 21;48(9):4976-4991. doi: 10.1093/nar/gkaa202. Nucleic Acids Res. 2020. PMID: 32232414 Free PMC article.

3

Drug discovery of small molecules targeting the higher-order hTERT promoter G-quadruplex.

Monsen RC, Maguire JM, DeLeeuw LW, Chaires JB, Trent JO. Monsen RC, et al. Among authors: deleeuw lw. PLoS One. 2022 Jun 16;17(6):e0270165. doi: 10.1371/journal.pone.0270165. eCollection 2022. PLoS One. 2022. PMID: 35709230 Free PMC article.

4

Putting a New Spin of G-Quadruplex Structure and Binding by Analytical Ultracentrifugation.

Dean WL, Gray RD, DeLeeuw L, Monsen RC, Chaires JB. Dean WL, et al. Methods Mol Biol. 2019;2035:87-103. doi: 10.1007/978-1-4939-9666-7_5. Methods Mol Biol. 2019. PMID: 31444745

5

Long promoter sequences form higher-order G-quadruplexes: an integrative structural biology study of c-Myc, k-Ras and c-Kit promoter sequences.

Monsen RC, DeLeeuw LW, Dean WL, Gray RD, Chakravarthy S, Hopkins JB, Chaires JB, Trent JO. Monsen RC, et al. Among authors: deleeuw lw. Nucleic Acids Res. 2022 Apr 22;50(7):4127-4147. doi: 10.1093/nar/gkac182. Nucleic Acids Res. 2022. PMID: 35325198 Free PMC article.

6

The hTERT core promoter forms three parallel G-quadruplexes.

Monsen RC, DeLeeuw L, Dean WL, Gray RD, Sabo TM, Chakravarthy S, Chaires JB, Trent JO. Monsen RC, et al. Nucleic Acids Res. 2020 Jun 4;48(10):5720-5734. doi: 10.1093/nar/gkaa107. Nucleic Acids Res. 2020. PMID: 32083666 Free PMC article.

7

Structural analysis of the DNA target site and its interaction with Mbp1.

Chernatynskaya AV, Deleeuw L, Trent JO, Brown T, Lane AN. Chernatynskaya AV, et al. Org Biomol Chem. 2009 Dec 7;7(23):4981-91. doi: 10.1039/b912309a. Epub 2009 Oct 7. Org Biomol Chem. 2009. PMID: 19907790

8

Activation of the proapoptotic Bcl-2 protein Bax by a small molecule induces tumor cell apoptosis.

Zhao G, Zhu Y, Eno CO, Liu Y, Deleeuw L, Burlison JA, Chaires JB, Trent JO, Li C. Zhao G, et al. Mol Cell Biol. 2014 Apr;34(7):1198-207. doi: 10.1128/MCB.00996-13. Epub 2014 Jan 13. Mol Cell Biol. 2014. PMID: 24421393 Free PMC article.

9

Clinical application of plasma thermograms. Utility, practical approaches and considerations.

Garbett NC, Mekmaysy CS, DeLeeuw L, Chaires JB. Garbett NC, et al. Methods. 2015 Apr;76:41-50. doi: 10.1016/j.ymeth.2014.10.030. Epub 2014 Nov 5. Methods. 2015. PMID: 25448297 Free PMC article.

10

Multi-group diagnostic classification of high-dimensional data using differential scanning calorimetry plasma thermograms.

Rai SN, Srivastava S, Pan J, Wu X, Rai SP, Mekmaysy CS, DeLeeuw L, Chaires JB, Garbett NC. Rai SN, et al. PLoS One. 2019 Aug 20;14(8):e0220765. doi: 10.1371/journal.pone.0220765. eCollection 2019. PLoS One. 2019. PMID: 31430304 Free PMC article.

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