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P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression.
Yeini E, Ofek P, Pozzi S, Albeck N, Ben-Shushan D, Tiram G, Golan S, Kleiner R, Sheinin R, Israeli Dangoor S, Reich-Zeliger S, Grossman R, Ram Z, Brem H, Hyde TM, Magod P, Friedmann-Morvinski D, Madi A, Satchi-Fainaro R. Yeini E, et al. Among authors: kleiner r. Nat Commun. 2021 Mar 26;12(1):1912. doi: 10.1038/s41467-021-22186-0. Nat Commun. 2021. PMID: 33771989 Free PMC article.
Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to immune checkpoint modulators.
Conniot J, Scomparin A, Peres C, Yeini E, Pozzi S, Matos AI, Kleiner R, Moura LIF, Zupančič E, Viana AS, Doron H, Gois PMP, Erez N, Jung S, Satchi-Fainaro R, Florindo HF. Conniot J, et al. Among authors: kleiner r. Nat Nanotechnol. 2019 Sep;14(9):891-901. doi: 10.1038/s41565-019-0512-0. Epub 2019 Aug 5. Nat Nanotechnol. 2019. PMID: 31384037
Immune-mediated approaches against COVID-19.
Florindo HF, Kleiner R, Vaskovich-Koubi D, Acúrcio RC, Carreira B, Yeini E, Tiram G, Liubomirski Y, Satchi-Fainaro R. Florindo HF, et al. Among authors: kleiner r. Nat Nanotechnol. 2020 Aug;15(8):630-645. doi: 10.1038/s41565-020-0732-3. Epub 2020 Jul 13. Nat Nanotechnol. 2020. PMID: 32661375 Free PMC article. Review.
Preclinical models and technologies to advance nanovaccine development.
Peres C, Matos AI, Moura LIF, Acúrcio RC, Carreira B, Pozzi S, Vaskovich-Koubi D, Kleiner R, Satchi-Fainaro R, Florindo HF. Peres C, et al. Among authors: kleiner r. Adv Drug Deliv Rev. 2021 May;172:148-182. doi: 10.1016/j.addr.2021.03.001. Epub 2021 Mar 9. Adv Drug Deliv Rev. 2021. PMID: 33711401 Review.
Meet me halfway: Are in vitro 3D cancer models on the way to replace in vivo models for nanomedicine development?
Pozzi S, Scomparin A, Israeli Dangoor S, Rodriguez Ajamil D, Ofek P, Neufeld L, Krivitsky A, Vaskovich-Koubi D, Kleiner R, Dey P, Koshrovski-Michael S, Reisman N, Satchi-Fainaro R. Pozzi S, et al. Among authors: kleiner r. Adv Drug Deliv Rev. 2021 Aug;175:113760. doi: 10.1016/j.addr.2021.04.001. Epub 2021 Apr 7. Adv Drug Deliv Rev. 2021. PMID: 33838208 Review.
Intranasal Multiepitope PD-L1-siRNA-Based Nanovaccine: The Next-Gen COVID-19 Immunotherapy.
Acúrcio RC, Kleiner R, Vaskovich-Koubi D, Carreira B, Liubomirski Y, Palma C, Yeheskel A, Yeini E, Viana AS, Ferreira V, Araújo C, Mor M, Freund NT, Bacharach E, Gonçalves J, Toister-Achituv M, Fabregue M, Matthieu S, Guerry C, Zarubica A, Aviel-Ronen S, Florindo HF, Satchi-Fainaro R. Acúrcio RC, et al. Among authors: kleiner r. Adv Sci (Weinh). 2024 Oct;11(40):e2404159. doi: 10.1002/advs.202404159. Epub 2024 Aug 8. Adv Sci (Weinh). 2024. PMID: 39116324 Free PMC article.
Two-in-one nanoparticle platform induces a strong therapeutic effect of targeted therapies in P-selectin-expressing cancers.
Koshrovski-Michael S, Ajamil DR, Dey P, Kleiner R, Tevet S, Epshtein Y, Green Buzhor M, Khoury R, Pozzi S, Shenbach-Koltin G, Yeini E, Woythe L, Blau R, Scomparin A, Barshack I, Florindo HF, Lazar S, Albertazzi L, Amir RJ, Satchi-Fainaro R. Koshrovski-Michael S, et al. Among authors: kleiner r. Sci Adv. 2024 Dec 13;10(50):eadr4762. doi: 10.1126/sciadv.adr4762. Epub 2024 Dec 13. Sci Adv. 2024. PMID: 39671487 Free PMC article.
Tailoring the lipid composition of nanoparticles modulates their cellular uptake and affects the viability of triple negative breast cancer cells.
Abumanhal-Masarweh H, da Silva D, Poley M, Zinger A, Goldman E, Krinsky N, Kleiner R, Shenbach G, Schroeder JE, Shklover J, Shainsky-Roitman J, Schroeder A. Abumanhal-Masarweh H, et al. Among authors: kleiner r. J Control Release. 2019 Aug 10;307:331-341. doi: 10.1016/j.jconrel.2019.06.025. Epub 2019 Jun 22. J Control Release. 2019. PMID: 31238049 Free PMC article.
173 results