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Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis.
Diesinger T, Buko V, Lautwein A, Dvorsky R, Belonovskaya E, Lukivskaya O, Naruta E, Kirko S, Andreev V, Buckert D, Bergler S, Renz C, Schneider E, Kuchenbauer F, Kumar M, Günes C, Büchele B, Simmet T, Müller-Enoch D, Wirth T, Haehner T. Diesinger T, et al. Among authors: dvorsky r. PLoS One. 2020 Jul 23;15(7):e0235990. doi: 10.1371/journal.pone.0235990. eCollection 2020. PLoS One. 2020. PMID: 32701948 Free PMC article.
A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma.
Diesinger T, Lautwein A, Bergler S, Buckert D, Renz C, Dvorsky R, Buko V, Kirko S, Schneider E, Kuchenbauer F, Kumar M, Günes C, Genze F, Büchele B, Simmet T, Haslbeck M, Masur K, Barth T, Müller-Enoch D, Wirth T, Haehner T. Diesinger T, et al. Among authors: dvorsky r. Can J Gastroenterol Hepatol. 2021 Feb 2;2021:8854432. doi: 10.1155/2021/8854432. eCollection 2021. Can J Gastroenterol Hepatol. 2021. PMID: 33604316 Free PMC article.
Selectivity Determinants of RHO GTPase Binding to IQGAPs.
Mosaddeghzadeh N, Nouri K, Krumbach OHF, Amin E, Dvorsky R, Ahmadian MR. Mosaddeghzadeh N, et al. Among authors: dvorsky r. Int J Mol Sci. 2021 Nov 22;22(22):12596. doi: 10.3390/ijms222212596. Int J Mol Sci. 2021. PMID: 34830479 Free PMC article.
New mechanistic insights into the RAS-SIN1 interaction at the membrane.
Pudewell S, Lissy J, Nakhaeizadeh H, Mosaddeghzadeh N, Nakhaei-Rad S, Dvorsky R, Ahmadian MR. Pudewell S, et al. Among authors: dvorsky r. Front Cell Dev Biol. 2022 Oct 6;10:987754. doi: 10.3389/fcell.2022.987754. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36274845 Free PMC article.
CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes.
Tiede I, Fritz G, Strand S, Poppe D, Dvorsky R, Strand D, Lehr HA, Wirtz S, Becker C, Atreya R, Mudter J, Hildner K, Bartsch B, Holtmann M, Blumberg R, Walczak H, Iven H, Galle PR, Ahmadian MR, Neurath MF. Tiede I, et al. Among authors: dvorsky r. J Clin Invest. 2003 Apr;111(8):1133-45. doi: 10.1172/JCI16432. J Clin Invest. 2003. PMID: 12697733 Free PMC article.
74 results