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Cytosolic sensing of immuno-stimulatory DNA, the enemy within.
Dhanwani R, Takahashi M, Sharma S. Dhanwani R, et al. Among authors: takahashi m. Curr Opin Immunol. 2018 Feb;50:82-87. doi: 10.1016/j.coi.2017.11.004. Epub 2017 Dec 13. Curr Opin Immunol. 2018. PMID: 29247853 Free PMC article. Review.
Cellular sensing of extracellular purine nucleosides triggers an innate IFN-β response.
Dhanwani R, Takahashi M, Mathews IT, Lenzi C, Romanov A, Watrous JD, Pieters B, Hedrick CC, Benedict CA, Linden J, Nilsson R, Jain M, Sharma S. Dhanwani R, et al. Among authors: takahashi m. Sci Adv. 2020 Jul 22;6(30):eaba3688. doi: 10.1126/sciadv.aba3688. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32743071 Free PMC article.
Leukocyte mono-immunoglobulin-like receptor 8 (LMIR8)/CLM-6 is an FcRγ-coupled receptor selectively expressed in mouse tissue plasmacytoid dendritic cells.
Kaitani A, Izawa K, Maehara A, Isobe M, Takamori A, Matsukawa T, Takahashi M, Yamanishi Y, Oki T, Yamada H, Nagamine M, Uchida S, Uchida K, Ando T, Maeda K, Nakano N, Shimizu T, Takai T, Ogawa H, Okumura K, Kitamura T, Kitaura J. Kaitani A, et al. Among authors: takahashi m. Sci Rep. 2018 May 29;8(1):8259. doi: 10.1038/s41598-018-25646-8. Sci Rep. 2018. PMID: 29844322 Free PMC article.
Sphingomyelin and ceramide are physiological ligands for human LMIR3/CD300f, inhibiting FcεRI-mediated mast cell activation.
Izawa K, Isobe M, Matsukawa T, Ito S, Maehara A, Takahashi M, Yamanishi Y, Kaitani A, Oki T, Okumura K, Kitamura T, Kitaura J. Izawa K, et al. Among authors: takahashi m. J Allergy Clin Immunol. 2014 Jan;133(1):270-3.e1-7. doi: 10.1016/j.jaci.2013.08.008. Epub 2013 Sep 12. J Allergy Clin Immunol. 2014. PMID: 24035150 No abstract available.
In vivo hyperphosphorylation of tau is associated with synaptic loss and behavioral abnormalities in the absence of tau seeds.
Watamura N, Foiani MS, Bez S, Bourdenx M, Santambrogio A, Frodsham C, Camporesi E, Brinkmalm G, Zetterberg H, Patel S, Kamano N, Takahashi M, Rueda-Carrasco J, Katsouri L, Fowler S, Turkes E, Hashimoto S, Sasaguri H, Saito T, Islam AS, Benner S, Endo T, Kobayashi K, Ishida C, Vendruscolo M, Yamada M, Duff KE, Saido TC. Watamura N, et al. Among authors: takahashi m. Nat Neurosci. 2024 Dec 24. doi: 10.1038/s41593-024-01829-7. Online ahead of print. Nat Neurosci. 2024. PMID: 39719507
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