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SVEP1 is a human coronary artery disease locus that promotes atherosclerosis.
Jung IH, Elenbaas JS, Alisio A, Santana K, Young EP, Kang CJ, Kachroo P, Lavine KJ, Razani B, Mecham RP, Stitziel NO. Jung IH, et al. Among authors: lavine kj. Sci Transl Med. 2021 Mar 24;13(586):eabe0357. doi: 10.1126/scitranslmed.abe0357. Sci Transl Med. 2021. PMID: 33762433 Free PMC article.
Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility.
Garg A, Jansen S, Zhang R, Lavine KJ, Greenberg MJ. Garg A, et al. Among authors: lavine kj. bioRxiv [Preprint]. 2024 Mar 12:2024.03.10.583979. doi: 10.1101/2024.03.10.583979. bioRxiv. 2024. Update in: Proc Natl Acad Sci U S A. 2024 Nov 12;121(46):e2405020121. doi: 10.1073/pnas.2405020121 PMID: 38559046 Free PMC article. Updated. Preprint.
Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation.
Epelman S, Lavine KJ, Beaudin AE, Sojka DK, Carrero JA, Calderon B, Brija T, Gautier EL, Ivanov S, Satpathy AT, Schilling JD, Schwendener R, Sergin I, Razani B, Forsberg EC, Yokoyama WM, Unanue ER, Colonna M, Randolph GJ, Mann DL. Epelman S, et al. Among authors: lavine kj. Immunity. 2014 Jan 16;40(1):91-104. doi: 10.1016/j.immuni.2013.11.019. Immunity. 2014. PMID: 24439267 Free PMC article.
Publisher Correction: Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction.
Dick SA, Macklin JA, Nejat S, Momen A, Clemente-Casares X, Althagafi MG, Chen J, Kantores C, Hosseinzadeh S, Aronoff L, Wong A, Zaman R, Barbu I, Besla R, Lavine KJ, Razani B, Ginhoux F, Husain M, Cybulsky MI, Robbins CS, Epelman S. Dick SA, et al. Among authors: lavine kj. Nat Immunol. 2019 May;20(5):664. doi: 10.1038/s41590-019-0363-8. Nat Immunol. 2019. PMID: 30862954
TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy.
Javaheri A, Bajpai G, Picataggi A, Mani S, Foroughi L, Evie H, Kovacs A, Weinheimer CJ, Hyrc K, Xiao Q, Ballabio A, Lee JM, Matkovich SJ, Razani B, Schilling JD, Lavine KJ, Diwan A. Javaheri A, et al. Among authors: lavine kj. JCI Insight. 2019 Nov 1;4(21):e127312. doi: 10.1172/jci.insight.127312. JCI Insight. 2019. PMID: 31672943 Free PMC article.
Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis.
Amrute JM, Luo X, Penna V, Bredemeyer A, Yamawaki T, Yang S, Kadyrov F, Heo GS, Shi SY, Lee P, Koenig AL, Kuppe C, Jones C, Kopecky B, Hayat S, Ma P, Terada Y, Fu A, Furtado M, Kreisel D, Stitziel NO, Li CM, Kramann R, Liu Y, Ason B, Lavine KJ. Amrute JM, et al. Among authors: lavine kj. Res Sq [Preprint]. 2023 Jan 26:rs.3.rs-2402606. doi: 10.21203/rs.3.rs-2402606/v1. Res Sq. 2023. Update in: Nature. 2024 Nov;635(8038):423-433. doi: 10.1038/s41586-024-08008-5 PMID: 36747878 Free PMC article. Updated. Preprint.
Targeting immune-fibroblast cell communication in heart failure.
Amrute JM, Luo X, Penna V, Yang S, Yamawaki T, Hayat S, Bredemeyer A, Jung IH, Kadyrov FF, Heo GS, Venkatesan R, Shi SY, Parvathaneni A, Koenig AL, Kuppe C, Baker C, Luehmann H, Jones C, Kopecky B, Zeng X, Bleckwehl T, Ma P, Lee P, Terada Y, Fu A, Furtado M, Kreisel D, Kovacs A, Stitziel NO, Jackson S, Li CM, Liu Y, Rosenthal NA, Kramann R, Ason B, Lavine KJ. Amrute JM, et al. Among authors: lavine kj. Nature. 2024 Nov;635(8038):423-433. doi: 10.1038/s41586-024-08008-5. Epub 2024 Oct 23. Nature. 2024. PMID: 39443792
146 results