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A public vaccine-induced human antibody protects against SARS-CoV-2 and emerging variants.
Schmitz AJ, Turner JS, Liu Z, Aziati ID, Chen RE, Joshi A, Bricker TL, Darling TL, Adelsberg DC, Alsoussi WB, Case JB, Lei T, Thapa M, Amanat F, O'Halloran JA, Shi PY, Presti RM, Krammer F, Bajic G, Whelan SPJ, Diamond MS, Boon ACM, Ellebedy AH. Schmitz AJ, et al. Among authors: shi py. bioRxiv [Preprint]. 2021 Mar 24:2021.03.24.436864. doi: 10.1101/2021.03.24.436864. bioRxiv. 2021. Update in: Immunity. 2021 Sep 14;54(9):2159-2166.e6. doi: 10.1016/j.immuni.2021.08.013 PMID: 33791696 Free PMC article. Updated. Preprint.
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs: a single molecule perspective.
Seifert M, Bera SC, van Nies P, Kirchdoerfer RN, Shannon A, Le TT, Meng X, Xia H, Wood JM, Harris LD, Papini FS, Arnold JJ, Almo SC, Grove TL, Shi PY, Xiang Y, Canard B, Depken M, Cameron CE, Dulin D. Seifert M, et al. Among authors: shi py. bioRxiv [Preprint]. 2021 Apr 8:2020.08.06.240325. doi: 10.1101/2020.08.06.240325. bioRxiv. 2021. Update in: Elife. 2021 Oct 07;10:e70968. doi: 10.7554/eLife.70968 PMID: 33851161 Free PMC article. Updated. Preprint.
CCR2-dependent monocyte-derived cells restrict SARS-CoV-2 infection.
Vanderheiden A, Thomas J, Soung AL, Davis-Gardner ME, Floyd K, Jin F, Cowan DA, Pellegrini K, Creanga A, Pegu A, Derrien-Colemyn A, Shi PY, Grakoui A, Klein RS, Bosinger SE, Kohlmeier JE, Menachery VD, Suthar MS. Vanderheiden A, et al. Among authors: shi py. bioRxiv [Preprint]. 2021 May 4:2021.05.03.442538. doi: 10.1101/2021.05.03.442538. bioRxiv. 2021. Update in: mBio. 2021 Dec 21;12(6):e0274921. doi: 10.1128/mBio.02749-21 PMID: 33972938 Free PMC article. Updated. Preprint.
Mouse Adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge.
Muruato A, Vu MN, Johnson BA, Davis-Gardner ME, Vanderheiden A, Lokugmage K, Schindewolf C, Crocquet-Valdes PA, Langsjoen RM, Plante JA, Plante KS, Weaver SC, Debbink K, Routh AL, Walker D, Suthar MS, Xie X, Shi PY, Xie X, Menachery VD. Muruato A, et al. Among authors: shi py. bioRxiv [Preprint]. 2021 May 4:2021.05.03.442357. doi: 10.1101/2021.05.03.442357. bioRxiv. 2021. Update in: PLoS Biol. 2021 Nov 4;19(11):e3001284. doi: 10.1371/journal.pbio.3001284 PMID: 33972939 Free PMC article. Updated. Preprint.
Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis.
Johnson BA, Zhou Y, Lokugamage KG, Vu MN, Bopp N, Crocquet-Valdes PA, Kalveram B, Schindewolf C, Liu Y, Scharton D, Plante JA, Xie X, Aguilar P, Weaver SC, Shi PY, Walker DH, Routh AL, Plante KS, Menachery VD. Johnson BA, et al. Among authors: shi py. bioRxiv [Preprint]. 2022 Mar 28:2021.10.14.464390. doi: 10.1101/2021.10.14.464390. bioRxiv. 2022. Update in: PLoS Pathog. 2022 Jun 21;18(6):e1010627. doi: 10.1371/journal.ppat.1010627 PMID: 34671771 Free PMC article. Updated. Preprint.
A modified porous silicon microparticle promotes mucosal delivery of SARS-CoV-2 antigen and induction of potent and durable systemic and mucosal T helper 1 skewed protective immunity.
Adam A, Shi Q, Wang B, Zou J, Mai J, Osman SR, Wu W, Xie X, Aguilar PV, Bao X, Shi PY, Shen H, Wang T. Adam A, et al. Among authors: shi q, shi py. bioRxiv [Preprint]. 2021 Nov 24:2021.11.22.469576. doi: 10.1101/2021.11.22.469576. bioRxiv. 2021. PMID: 34845456 Free PMC article. Preprint.
Engineering SARS-CoV-2 cocktail antibodies into a bispecific format improves neutralizing potency and breadth.
Ku Z, Xie X, Lin J, Gao P, El Sahili A, Su H, Liu Y, Ye X, Li X, Fan X, Goh BC, Xiong W, Boyd H, Muruato AE, Deng H, Xia H, Jing Z, Kalveram BK, Menachery VD, Zhang N, Lescar J, Shi PY, An Z. Ku Z, et al. Among authors: shi py. bioRxiv [Preprint]. 2022 Feb 1:2022.02.01.478504. doi: 10.1101/2022.02.01.478504. bioRxiv. 2022. Update in: Nat Commun. 2022 Sep 22;13(1):5552. doi: 10.1038/s41467-022-33284-y PMID: 35132410 Free PMC article. Updated. Preprint.
479 results