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A Phase I Evaluation of the Pharmacokinetics and Tolerability of the HIV-1 Maturation Inhibitor GSK3640254 and Tenofovir Alafenamide/Emtricitabine in Healthy Participants.
Pene Dumitrescu T, Joshi SR, Xu J, Zhan J, Johnson M, Butcher L, Zimmerman E, Webster L, Davidson AM, Lataillade M, Min S. Pene Dumitrescu T, et al. Among authors: zhan j. Antimicrob Agents Chemother. 2021 May 18;65(6):e02173-20. doi: 10.1128/AAC.02173-20. Print 2021 May 18. Antimicrob Agents Chemother. 2021. PMID: 33753329 Free PMC article. Clinical Trial.
Phase IIa Proof-of-Concept Evaluation of the Antiviral Efficacy, Safety, Tolerability, and Pharmacokinetics of the Next-Generation Maturation Inhibitor GSK3640254.
Spinner CD, Felizarta F, Rizzardini G, Philibert P, Mitha E, Domingo P, Stephan CJ, DeGrosky M, Bainbridge V, Zhan J, Dumitrescu TP, Jeffrey JL, Xu J, Halliday F, Gan J, Johnson M, Gartland M, Joshi SR, Lataillade M. Spinner CD, et al. Among authors: zhan j. Clin Infect Dis. 2022 Sep 14;75(5):786-794. doi: 10.1093/cid/ciab1065. Clin Infect Dis. 2022. PMID: 34996113 Free PMC article. Clinical Trial.
Investigation of Clinical Absorption, Distribution, Metabolism, and Excretion and Pharmacokinetics of the HIV-1 Maturation Inhibitor GSK3640254 Using an Intravenous Microtracer Combined with EnteroTracker for Biliary Sampling.
Wen B, Zhang Y, Young GC, Kenworthy D, Pereira A, Pirhalla J, Doyle J, Jordon B, Zhan J, Johnson M. Wen B, et al. Among authors: zhan j. Drug Metab Dispos. 2022 Nov;50(11):1442-1453. doi: 10.1124/dmd.122.000955. Epub 2022 Sep 24. Drug Metab Dispos. 2022. PMID: 36153007 Clinical Trial.
2,677 results