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A Phase I Evaluation of the Pharmacokinetics and Tolerability of the HIV-1 Maturation Inhibitor GSK3640254 and Tenofovir Alafenamide/Emtricitabine in Healthy Participants.
Pene Dumitrescu T, Joshi SR, Xu J, Zhan J, Johnson M, Butcher L, Zimmerman E, Webster L, Davidson AM, Lataillade M, Min S. Pene Dumitrescu T, et al. Among authors: butcher l. Antimicrob Agents Chemother. 2021 May 18;65(6):e02173-20. doi: 10.1128/AAC.02173-20. Print 2021 May 18. Antimicrob Agents Chemother. 2021. PMID: 33753329 Free PMC article. Clinical Trial.
Phase I evaluation of pharmacokinetics and tolerability of the HIV-1 maturation inhibitor GSK3640254 and dolutegravir in healthy adults.
Pene Dumitrescu T, Joshi SR, Xu J, Greene TJ, Johnson M, Butcher L, Zimmerman E, Webster L, Pham TT, Lataillade M, Min S. Pene Dumitrescu T, et al. Among authors: butcher l. Br J Clin Pharmacol. 2021 Sep;87(9):3501-3507. doi: 10.1111/bcp.14759. Epub 2021 Mar 4. Br J Clin Pharmacol. 2021. PMID: 33533507 Free PMC article. Clinical Trial.
Lack of pharmacokinetic interaction between the HIV-1 maturation inhibitor GSK3640254 and combination oral contraceptives in healthy women.
Pene Dumitrescu T, Greene TJ, Joshi SR, Xu J, Johnson M, Halliday F, Butcher L, Zimmerman E, Webster L, Pham TT, Lataillade M, Min S. Pene Dumitrescu T, et al. Among authors: butcher l. Br J Clin Pharmacol. 2022 Feb;88(4):1704-1712. doi: 10.1111/bcp.15051. Epub 2021 Sep 21. Br J Clin Pharmacol. 2022. PMID: 34427938 Free PMC article.
Non-clinical and first-in-human characterization of ECC5004/AZD5004, a novel once-daily, oral small-molecule GLP-1 receptor agonist.
Haggag AZ, Xu J, Butcher L, Pagnussat S, Davies G, Lundqvist S, Wang W, Van Zuydam N, Nelander K, Jha A, Yu H, Boianelli A, Lindmark B, Ollerstam A, Sun X, Wang F, Pan X, Liu H, Chen W, Xu J, Wallenius K, Zhou J. Haggag AZ, et al. Among authors: butcher l. Diabetes Obes Metab. 2025 Feb;27(2):551-562. doi: 10.1111/dom.16047. Epub 2024 Nov 4. Diabetes Obes Metab. 2025. PMID: 39495140 Free PMC article. Clinical Trial.
464 results