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Deciphering structural bases of intestinal and hepatic selectivity in targeting pregnane X receptor with indole-based microbial mimics.
Li H, Illés P, Karunaratne CV, Nordstrøm LU, Luo X, Yang A, Qiu Y, Kurland IJ, Lukin DJ, Chen W, Jiskrová E, Krasulová K, Pečinková P, DesMarais VM, Liu Q, Albanese JM, Akki A, Longo M, Coffin B, Dou W, Mani S, Dvořák Z. Li H, et al. Among authors: albanese jm. Bioorg Chem. 2021 Apr;109:104661. doi: 10.1016/j.bioorg.2021.104661. Epub 2021 Jan 22. Bioorg Chem. 2021. PMID: 33636438 Free PMC article.
Functional succinate dehydrogenase deficiency is a common adverse feature of clear cell renal cancer.
Aggarwal RK, Luchtel RA, Machha V, Tischer A, Zou Y, Pradhan K, Ashai N, Ramachandra N, Albanese JM, Yang JI, Wang X, Aluri S, Gordon S, Aboumohamed A, Gartrell BA, Hafizi S, Pullman J, Shenoy N. Aggarwal RK, et al. Among authors: albanese jm. Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2106947118. doi: 10.1073/pnas.2106947118. Proc Natl Acad Sci U S A. 2021. PMID: 34551979 Free PMC article.
254 results