van Vugt MATM - Search Results

1

Shaping the BRCAness mutational landscape by alternative double-strand break repair, replication stress and mitotic aberrancies.

Stok C, Kok YP, van den Tempel N, van Vugt MATM. Stok C, et al. Among authors: van vugt matm, van den tempel n. Nucleic Acids Res. 2021 May 7;49(8):4239-4257. doi: 10.1093/nar/gkab151. Nucleic Acids Res. 2021. PMID: 33744950 Free PMC article. Review.

2

The DNA damage response during mitosis.

Heijink AM, Krajewska M, van Vugt MA. Heijink AM, et al. Mutat Res. 2013 Oct;750(1-2):45-55. doi: 10.1016/j.mrfmmm.2013.07.003. Epub 2013 Jul 21. Mutat Res. 2013. PMID: 23880065 Review.

3

Therapeutic targeting and patient selection for cancers with homologous recombination defects.

Talens F, Jalving M, Gietema JA, Van Vugt MA. Talens F, et al. Expert Opin Drug Discov. 2017 Jun;12(6):565-581. doi: 10.1080/17460441.2017.1322061. Epub 2017 May 2. Expert Opin Drug Discov. 2017. PMID: 28425306 Free article. Review.

4

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells.

Schoonen PM, Talens F, Stok C, Gogola E, Heijink AM, Bouwman P, Foijer F, Tarsounas M, Blatter S, Jonkers J, Rottenberg S, van Vugt MATM. Schoonen PM, et al. Among authors: van vugt matm. Nat Commun. 2017 Jul 17;8:15981. doi: 10.1038/ncomms15981. Nat Commun. 2017. PMID: 28714471 Free PMC article.

5

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells.

van Gijn SE, Wierenga E, van den Tempel N, Kok YP, Heijink AM, Spierings DCJ, Foijer F, van Vugt MATM, Fehrmann RSN. van Gijn SE, et al. Among authors: van vugt matm, van den tempel n. Oncogene. 2019 Feb;38(6):852-867. doi: 10.1038/s41388-018-0470-2. Epub 2018 Sep 3. Oncogene. 2019. PMID: 30177840 Free PMC article.

6

Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity.

Heijink AM, Everts M, Honeywell ME, Richards R, Kok YP, de Vries EGE, Lee MJ, van Vugt MATM. Heijink AM, et al. Among authors: van vugt matm. Cell Rep. 2019 Aug 27;28(9):2345-2357.e5. doi: 10.1016/j.celrep.2019.07.070. Cell Rep. 2019. PMID: 31461651 Free PMC article.

7

Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition-mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2-deficient cancer cells.

Schoonen PM, Kok YP, Wierenga E, Bakker B, Foijer F, Spierings DCJ, van Vugt MATM. Schoonen PM, et al. Among authors: van vugt matm. Mol Oncol. 2019 Nov;13(11):2422-2440. doi: 10.1002/1878-0261.12573. Epub 2019 Oct 21. Mol Oncol. 2019. PMID: 31529615 Free PMC article.

8

The RECQL helicase prevents replication fork collapse during replication stress.

Benedict B, van Bueren MA, van Gemert FP, Lieftink C, Guerrero Llobet S, van Vugt MA, Beijersbergen RL, Te Riele H. Benedict B, et al. Life Sci Alliance. 2020 Aug 20;3(10):e202000668. doi: 10.26508/lsa.202000668. Print 2020 Oct. Life Sci Alliance. 2020. PMID: 32820027 Free PMC article.

9

Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors.

Kok YP, Guerrero Llobet S, Schoonen PM, Everts M, Bhattacharya A, Fehrmann RSN, van den Tempel N, van Vugt MATM. Kok YP, et al. Among authors: van vugt matm, van den tempel n. Oncogenesis. 2020 Oct 7;9(10):88. doi: 10.1038/s41389-020-00270-2. Oncogenesis. 2020. PMID: 33028815 Free PMC article.

10

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.

Geijer ME, Zhou D, Selvam K, Steurer B, Mukherjee C, Evers B, Cugusi S, van Toorn M, van der Woude M, Janssens RC, Kok YP, Gong W, Raams A, Lo CSY, Lebbink JHG, Geverts B, Plummer DA, Bezstarosti K, Theil AF, Mitter R, Houtsmuller AB, Vermeulen W, Demmers JAA, Li S, van Vugt MATM, Lans H, Bernards R, Svejstrup JQ, Ray Chaudhuri A, Wyrick JJ, Marteijn JA. Geijer ME, et al. Among authors: van vugt matm, van der woude m, van toorn m. Nat Cell Biol. 2021 Jun;23(6):608-619. doi: 10.1038/s41556-021-00692-z. Epub 2021 Jun 9. Nat Cell Biol. 2021. PMID: 34108662 Free PMC article.

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