Heales SJR - Search Results

1

Aromatic l-amino acid decarboxylase deficiency: a patient-derived neuronal model for precision therapies.

Rossignoli G, Krämer K, Lugarà E, Alrashidi H, Pope S, De La Fuente Barrigon C, Barwick K, Bisello G, Ng J, Counsell J, Lignani G, Heales SJR, Bertoldi M, Barral S, Kurian MA. Rossignoli G, et al. Among authors: heales sjr. Brain. 2021 Sep 4;144(8):2443-2456. doi: 10.1093/brain/awab123. Brain. 2021. PMID: 33734312 Free PMC article.

2

Astrocytes protect against copper-catalysed loss of extracellular glutathione.

Pope SA, Milton R, Heales SJ. Pope SA, et al. Neurochem Res. 2008 Jul;33(7):1410-8. doi: 10.1007/s11064-008-9602-3. Epub 2008 Mar 12. Neurochem Res. 2008. PMID: 18335314

3

Oxidative stress and mitochondrial dysfunction in neurodegeneration; cardiolipin a critical target?

Pope S, Land JM, Heales SJ. Pope S, et al. Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):794-9. doi: 10.1016/j.bbabio.2008.03.011. Epub 2008 Mar 29. Biochim Biophys Acta. 2008. PMID: 18420023 Free article. Review.

4

Mitochondrial cytochrome c release: a factor to consider in mitochondrial disease?

Oppenheim ML, Hargreaves IP, Pope S, Land JM, Heales SJ. Oppenheim ML, et al. J Inherit Metab Dis. 2009 Apr;32(2):269-73. doi: 10.1007/s10545-009-1061-8. Epub 2009 Jan 26. J Inherit Metab Dis. 2009. PMID: 19169843

5

A new perspective on the treatment of aromatic L-amino acid decarboxylase deficiency.

Allen GF, Land JM, Heales SJ. Allen GF, et al. Mol Genet Metab. 2009 May;97(1):6-14. doi: 10.1016/j.ymgme.2009.01.010. Epub 2009 Jan 27. Mol Genet Metab. 2009. PMID: 19231266 Review.

6

Pyridoxal 5'-phosphate deficiency causes a loss of aromatic L-amino acid decarboxylase in patients and human neuroblastoma cells, implications for aromatic L-amino acid decarboxylase and vitamin B(6) deficiency states.

Allen GF, Neergheen V, Oppenheim M, Fitzgerald JC, Footitt E, Hyland K, Clayton PT, Land JM, Heales SJ. Allen GF, et al. J Neurochem. 2010 Jul;114(1):87-96. doi: 10.1111/j.1471-4159.2010.06742.x. Epub 2010 Apr 9. J Neurochem. 2010. PMID: 20403077 Free article.

7

Dopamine but not l-dopa stimulates neural glutathione metabolism. Potential implications for Parkinson's and other dopamine deficiency states.

Allen GF, Ullah Y, Hargreaves IP, Land JM, Heales SJ. Allen GF, et al. Neurochem Int. 2013 Apr;62(5):684-94. doi: 10.1016/j.neuint.2012.12.004. Epub 2012 Dec 19. Neurochem Int. 2013. PMID: 23261515

8

Dysregulation of glucose metabolism is an early event in sporadic Parkinson's disease.

Dunn L, Allen GF, Mamais A, Ling H, Li A, Duberley KE, Hargreaves IP, Pope S, Holton JL, Lees A, Heales SJ, Bandopadhyay R. Dunn L, et al. Neurobiol Aging. 2014 May;35(5):1111-5. doi: 10.1016/j.neurobiolaging.2013.11.001. Epub 2013 Nov 9. Neurobiol Aging. 2014. PMID: 24300239 Free PMC article.

9

Clinical features and pharmacotherapy of childhood monoamine neurotransmitter disorders.

Ng J, Heales SJ, Kurian MA. Ng J, et al. Paediatr Drugs. 2014 Aug;16(4):275-91. doi: 10.1007/s40272-014-0079-z. Paediatr Drugs. 2014. PMID: 25011953 Free PMC article. Review.

10

Monoamine neurotransmitter disorders--clinical advances and future perspectives.

Ng J, Papandreou A, Heales SJ, Kurian MA. Ng J, et al. Nat Rev Neurol. 2015 Oct;11(10):567-84. doi: 10.1038/nrneurol.2015.172. Epub 2015 Sep 22. Nat Rev Neurol. 2015. PMID: 26392380 Review.

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