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Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Shi Y, Murzin AG, Falcon B, Epstein A, Machin J, Tempest P, Newell KL, Vidal R, Garringer HJ, Sahara N, Higuchi M, Ghetti B, Jang MK, Scheres SHW, Goedert M. Shi Y, et al. Among authors: scheres shw. Acta Neuropathol. 2021 May;141(5):697-708. doi: 10.1007/s00401-021-02294-3. Epub 2021 Mar 16. Acta Neuropathol. 2021. PMID: 33723967 Free PMC article.
How cryo-EM is revolutionizing structural biology.
Bai XC, McMullan G, Scheres SH. Bai XC, et al. Trends Biochem Sci. 2015 Jan;40(1):49-57. doi: 10.1016/j.tibs.2014.10.005. Epub 2014 Nov 7. Trends Biochem Sci. 2015. PMID: 25544475 Review.
Cryo-EM structures of tau filaments from Alzheimer's disease.
Fitzpatrick AWP, Falcon B, He S, Murzin AG, Murshudov G, Garringer HJ, Crowther RA, Ghetti B, Goedert M, Scheres SHW. Fitzpatrick AWP, et al. Among authors: scheres shw. Nature. 2017 Jul 13;547(7662):185-190. doi: 10.1038/nature23002. Epub 2017 Jul 5. Nature. 2017. PMID: 28678775 Free PMC article.
Structures of filaments from Pick's disease reveal a novel tau protein fold.
Falcon B, Zhang W, Murzin AG, Murshudov G, Garringer HJ, Vidal R, Crowther RA, Ghetti B, Scheres SHW, Goedert M. Falcon B, et al. Among authors: scheres shw. Nature. 2018 Sep;561(7721):137-140. doi: 10.1038/s41586-018-0454-y. Epub 2018 Aug 29. Nature. 2018. PMID: 30158706 Free PMC article.
145 results