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Advanced therapeutic inhalation aerosols of a Nrf2 activator and RhoA/Rho kinase (ROCK) inhibitor for targeted pulmonary drug delivery in pulmonary hypertension: design, characterization, aerosolization, in vitro 2D/3D human lung cell cultures, and in vivo efficacy.
Acosta MF, Muralidharan P, Grijalva CL, Abrahamson MD, Hayes D Jr, Fineman JR, Black SM, Mansour HM. Acosta MF, et al. Ther Adv Respir Dis. 2021 Jan-Dec;15:1753466621998245. doi: 10.1177/1753466621998245. Ther Adv Respir Dis. 2021. PMID: 33719747 Free PMC article.
Comparison of l-Carnitine and l-Carnitine HCL salt for targeted lung treatment of pulmonary hypertension (PH) as inhalation aerosols: Design, comprehensive characterization, in vitro 2D/3D cell cultures, and in vivo MCT-Rat model of PH.
Acosta MF, Muralidhran P, Abrahamson MD, Grijalva CL, Carver M, Tang H, Klinger C, Fineman JR, Black SM, Mansour HM. Acosta MF, et al. Pulm Pharmacol Ther. 2020 Dec;65:101998. doi: 10.1016/j.pupt.2021.101998. Epub 2021 Feb 5. Pulm Pharmacol Ther. 2020. PMID: 33556627 Free PMC article.
Design and Comprehensive Characterization of Tetramethylpyrazine (TMP) for Targeted Lung Delivery as Inhalation Aerosols in Pulmonary Hypertension (PH): In Vitro Human Lung Cell Culture and In Vivo Efficacy.
Muralidharan P, Acosta MF, Gomez AI, Grijalva C, Tang H, Yuan JX, Mansour HM. Muralidharan P, et al. Among authors: acosta mf. Antioxidants (Basel). 2021 Mar 11;10(3):427. doi: 10.3390/antiox10030427. Antioxidants (Basel). 2021. PMID: 33799587 Free PMC article.
Synthesis, Physicochemical Characterization, In Vitro 2D/3D Human Cell Culture, and In Vitro Aerosol Dispersion Performance of Advanced Spray Dried and Co-Spray Dried Angiotensin (1-7) Peptide and PNA5 with Trehalose as Microparticles/Nanoparticles for Targeted Respiratory Delivery as Dry Powder Inhalers.
Alabsi W, Acosta MF, Al-Obeidi FA, Hay M, Polt R, Mansour HM. Alabsi W, et al. Among authors: acosta mf. Pharmaceutics. 2021 Aug 17;13(8):1278. doi: 10.3390/pharmaceutics13081278. Pharmaceutics. 2021. PMID: 34452239 Free PMC article.
16 results