Bose K - Search Results

1

Loss of GSK-3β mediated phosphorylation in HtrA2 contributes to uncontrolled cell death with Parkinsonian phenotype.

Bose K, Wagh A, Mishra V, Dutta S, Parui AL, Puja R, Mudrale SP, Kulkarni SS, Gai PB, Sarin R. Bose K, et al. Int J Biol Macromol. 2021 Jun 1;180:97-111. doi: 10.1016/j.ijbiomac.2021.03.040. Epub 2021 Mar 12. Int J Biol Macromol. 2021. PMID: 33716130

2

Allosteric regulation of serine protease HtrA2 through novel non-canonical substrate binding pocket.

Bejugam PR, Kuppili RR, Singh N, Gadewal N, Chaganti LK, Sastry GM, Bose K. Bejugam PR, et al. Among authors: bose k. PLoS One. 2013;8(2):e55416. doi: 10.1371/journal.pone.0055416. Epub 2013 Feb 14. PLoS One. 2013. PMID: 23457469 Free PMC article.

3

Intricate structural coordination and domain plasticity regulate activity of serine protease HtrA2.

Chaganti LK, Kuppili RR, Bose K. Chaganti LK, et al. Among authors: bose k. FASEB J. 2013 Aug;27(8):3054-66. doi: 10.1096/fj.13-227256. Epub 2013 Apr 22. FASEB J. 2013. PMID: 23608143

4

Dual regulatory switch confers tighter control on HtrA2 proteolytic activity.

Singh N, D'Souza A, Cholleti A, Sastry GM, Bose K. Singh N, et al. Among authors: bose k. FEBS J. 2014 May;281(10):2456-70. doi: 10.1111/febs.12799. Epub 2014 Apr 22. FEBS J. 2014. PMID: 24698088 Free article.

5

Structural basis of inactivation of human counterpart of mouse motor neuron degeneration 2 mutant in serine protease HtrA2.

Wagh AR, Bose K. Wagh AR, et al. Among authors: bose k. Biosci Rep. 2018 Oct 5;38(5):BSR20181072. doi: 10.1042/BSR20181072. Print 2018 Oct 31. Biosci Rep. 2018. PMID: 30068699 Free PMC article.

6

Discerning the mechanism of action of HtrA4: a serine protease implicated in the cell death pathway.

Kummari R, Dutta S, Chaganti LK, Bose K. Kummari R, et al. Among authors: bose k. Biochem J. 2019 May 21;476(10):1445-1463. doi: 10.1042/BCJ20190224. Biochem J. 2019. PMID: 31036715

7

Identification of a distal allosteric ligand binding pocket in HtrA3.

Acharya S, Dutta S, Chopra S, Bose K. Acharya S, et al. Among authors: bose k. Biochem Biophys Res Commun. 2019 Sep 3;516(4):1130-1136. doi: 10.1016/j.bbrc.2019.07.005. Epub 2019 Jul 5. Biochem Biophys Res Commun. 2019. PMID: 31280864

8

Structural modeling and role of HAX-1 as a positive allosteric modulator of human serine protease HtrA2.

Chaganti LK, Dutta S, Kuppili RR, Mandal M, Bose K. Chaganti LK, et al. Among authors: bose k. Biochem J. 2019 Oct 30;476(20):2965-2980. doi: 10.1042/BCJ20190569. Biochem J. 2019. PMID: 31548268

9

A distinct concerted mechanism of structural dynamism defines activity of human serine protease HtrA3.

Acharya S, Dutta S, Bose K. Acharya S, et al. Among authors: bose k. Biochem J. 2020 Jan 31;477(2):407-429. doi: 10.1042/BCJ20190706. Biochem J. 2020. PMID: 31899476 Free PMC article.

10

Dual specificity phosphatase 9: A novel binding partner cum substrate of proapoptotic serine protease HtrA2.

Acharya S, Dutta S, Mudrale SP, Bose K. Acharya S, et al. Among authors: bose k. Biochem Biophys Res Commun. 2020 Dec 10;533(3):607-612. doi: 10.1016/j.bbrc.2020.09.062. Epub 2020 Sep 26. Biochem Biophys Res Commun. 2020. PMID: 32988583

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