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Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label treatment.
Hirt CK, Booij TH, Grob L, Simmler P, Toussaint NC, Keller D, Taube D, Ludwig V, Goryachkin A, Pauli C, Lenggenhager D, Stekhoven DJ, Stirnimann CU, Endhardt K, Ringnalda F, Villiger L, Siebenhüner A, Karkampouna S, De Menna M, Beshay J, Klett H, Kruithof-de Julio M, Schüler J, Schwank G. Hirt CK, et al. Cell Genom. 2022 Feb;2(2):100095. doi: 10.1016/j.xgen.2022.100095. Cell Genom. 2022. PMID: 35187519 Free PMC article.
Bladder cancer organoids as a functional system to model different disease stages and therapy response.
Minoli M, Cantore T, Hanhart D, Kiener M, Fedrizzi T, La Manna F, Karkampouna S, Chouvardas P, Genitsch V, Rodriguez-Calero A, Compérat E, Klima I, Gasperini P, Kiss B, Seiler R, Demichelis F, Thalmann GN, Kruithof-de Julio M. Minoli M, et al. Nat Commun. 2023 Apr 18;14(1):2214. doi: 10.1038/s41467-023-37696-2. Nat Commun. 2023. PMID: 37072390 Free PMC article.
Cationic amphiphilic drugs as potential anticancer therapy for bladder cancer.
van der Horst G, van de Merbel AF, Ruigrok E, van der Mark MH, Ploeg E, Appelman L, Tvingsholm S, Jäätelä M, van Uhm J, Kruithof-de Julio M, Thalmann GN, Pelger RCM, Bangma CH, Boormans JL, van der Pluijm G, Zwarthoff EC. van der Horst G, et al. Mol Oncol. 2020 Dec;14(12):3121-3134. doi: 10.1002/1878-0261.12793. Epub 2020 Oct 16. Mol Oncol. 2020. PMID: 32896947 Free PMC article.
Patient-derived xenografts and organoids model therapy response in prostate cancer.
Karkampouna S, La Manna F, Benjak A, Kiener M, De Menna M, Zoni E, Grosjean J, Klima I, Garofoli A, Bolis M, Vallerga A, Theurillat JP, De Filippo MR, Genitsch V, Keller D, Booij TH, Stirnimann CU, Eng K, Sboner A, Ng CKY, Piscuoglio S, Gray PC, Spahn M, Rubin MA, Thalmann GN, Kruithof-de Julio M. Karkampouna S, et al. Nat Commun. 2021 Feb 18;12(1):1117. doi: 10.1038/s41467-021-21300-6. Nat Commun. 2021. PMID: 33602919 Free PMC article.
Therapeutic Targeting of CD146/MCAM Reduces Bone Metastasis in Prostate Cancer.
Zoni E, Astrologo L, Ng CKY, Piscuoglio S, Melsen J, Grosjean J, Klima I, Chen L, Snaar-Jagalska EB, Flanagan K, van der Pluijm G, Kloen P, Cecchini MG, Kruithof-de Julio M, Thalmann GN. Zoni E, et al. Mol Cancer Res. 2019 May;17(5):1049-1062. doi: 10.1158/1541-7786.MCR-18-1220. Epub 2019 Feb 11. Mol Cancer Res. 2019. PMID: 30745464 Free article.
93 results