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FUS-dependent liquid-liquid phase separation is important for DNA repair initiation.
Levone BR, Lenzken SC, Antonaci M, Maiser A, Rapp A, Conte F, Reber S, Mechtersheimer J, Ronchi AE, Mühlemann O, Leonhardt H, Cardoso MC, Ruepp MD, Barabino SML. Levone BR, et al. Among authors: ruepp md. J Cell Biol. 2021 May 3;220(5):e202008030. doi: 10.1083/jcb.202008030. J Cell Biol. 2021. PMID: 33704371 Free PMC article.
FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factors.
Raczynska KD, Ruepp MD, Brzek A, Reber S, Romeo V, Rindlisbacher B, Heller M, Szweykowska-Kulinska Z, Jarmolowski A, Schümperli D. Raczynska KD, et al. Among authors: ruepp md. Nucleic Acids Res. 2015 Nov 16;43(20):9711-28. doi: 10.1093/nar/gkv794. Epub 2015 Aug 6. Nucleic Acids Res. 2015. PMID: 26250115 Free PMC article.
Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS.
Suárez-Calvet M, Neumann M, Arzberger T, Abou-Ajram C, Funk E, Hartmann H, Edbauer D, Kremmer E, Göbl C, Resch M, Bourgeois B, Madl T, Reber S, Jutzi D, Ruepp MD, Mackenzie IR, Ansorge O, Dormann D, Haass C. Suárez-Calvet M, et al. Among authors: ruepp md. Acta Neuropathol. 2016 Apr;131(4):587-604. doi: 10.1007/s00401-016-1544-2. Epub 2016 Feb 19. Acta Neuropathol. 2016. PMID: 26895297 Free article.
45 results