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Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications.
Highland JN, Zanos P, Riggs LM, Georgiou P, Clark SM, Morris PJ, Moaddel R, Thomas CJ, Zarate CA Jr, Pereira EFR, Gould TD. Highland JN, et al. Among authors: georgiou p. Pharmacol Rev. 2021 Apr;73(2):763-791. doi: 10.1124/pharmrev.120.000149. Pharmacol Rev. 2021. PMID: 33674359 Free PMC article. Review.
NMDAR inhibition-independent antidepressant actions of ketamine metabolites.
Zanos P, Moaddel R, Morris PJ, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KS, Fang Y, Huang XP, Mayo CL, Wainer IW, Albuquerque EX, Thompson SM, Thomas CJ, Zarate CA Jr, Gould TD. Zanos P, et al. Among authors: georgiou p. Nature. 2016 May 26;533(7604):481-6. doi: 10.1038/nature17998. Epub 2016 May 4. Nature. 2016. PMID: 27144355 Free PMC article.
Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations.
Le NT, Chang L, Kovlyagina I, Georgiou P, Safren N, Braunstein KE, Kvarta MD, Van Dyke AM, LeGates TA, Philips T, Morrison BM, Thompson SM, Puche AC, Gould TD, Rothstein JD, Wong PC, Monteiro MJ. Le NT, et al. Among authors: georgiou p. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7580-E7589. doi: 10.1073/pnas.1608432113. Epub 2016 Nov 9. Proc Natl Acad Sci U S A. 2016. PMID: 27834214 Free PMC article.
A Negative Allosteric Modulator for α5 Subunit-Containing GABA Receptors Exerts a Rapid and Persistent Antidepressant-Like Action without the Side Effects of the NMDA Receptor Antagonist Ketamine in Mice.
Zanos P, Nelson ME, Highland JN, Krimmel SR, Georgiou P, Gould TD, Thompson SM. Zanos P, et al. Among authors: georgiou p. eNeuro. 2017 Mar 7;4(1):ENEURO.0285-16.2017. doi: 10.1523/ENEURO.0285-16.2017. eCollection 2017 Jan-Feb. eNeuro. 2017. PMID: 28275719 Free PMC article.
Oxytocin and opioid addiction revisited: old drug, new applications.
Zanos P, Georgiou P, Weber C, Robinson F, Kouimtsidis C, Niforooshan R, Bailey A. Zanos P, et al. Among authors: georgiou p. Br J Pharmacol. 2018 Jul;175(14):2809-2824. doi: 10.1111/bph.13757. Epub 2017 Apr 6. Br J Pharmacol. 2018. PMID: 28378414 Free PMC article. Review.
397 results