Pedicone C - Search Results

1

Pedicone C, Meyer ST, Chisholm JD, Kerr WG. Pedicone C, et al. Cancers (Basel). 2021 Feb 20;13(4):890. doi: 10.3390/cancers13040890. Cancers (Basel). 2021. PMID: 33672717 Free PMC article. Review.

2

Pan-SHIP1/2 inhibitors promote microglia effector functions essential for CNS homeostasis.

Pedicone C, Fernandes S, Dungan OM, Dormann SM, Viernes DR, Adhikari AA, Choi LB, De Jong EP, Chisholm JD, Kerr WG. Pedicone C, et al. J Cell Sci. 2020 Jan 10;133(5):jcs238030. doi: 10.1242/jcs.238030. J Cell Sci. 2020. PMID: 31780579 Free PMC article.

3

Small molecule targeting of SHIP1 and SHIP2.

Kerr WG, Pedicone C, Dormann S, Pacherille A, Chisholm JD. Kerr WG, et al. Among authors: pedicone c. Biochem Soc Trans. 2020 Feb 28;48(1):291-300. doi: 10.1042/BST20190775. Biochem Soc Trans. 2020. PMID: 32049315 Review.

4

Discovery of a novel SHIP1 agonist that promotes degradation of lipid-laden phagocytic cargo by microglia.

Pedicone C, Fernandes S, Matera A, Meyer ST, Loh S, Ha JH, Bernard D, Chisholm JD, Paolicelli RC, Kerr WG. Pedicone C, et al. iScience. 2022 Mar 26;25(4):104170. doi: 10.1016/j.isci.2022.104170. eCollection 2022 Apr 15. iScience. 2022. PMID: 35465359 Free PMC article.

5

LRBA Deficiency Can Lead to Lethal Colitis That Is Diminished by SHIP1 Agonism.

Sudan R, Fernandes S, Srivastava N, Pedicone C, Meyer ST, Chisholm JD, Engelman RW, Kerr WG. Sudan R, et al. Among authors: pedicone c. Front Immunol. 2022 May 4;13:830961. doi: 10.3389/fimmu.2022.830961. eCollection 2022. Front Immunol. 2022. PMID: 35603158 Free PMC article.

6

Obesity control by SHIP inhibition requires pan-paralog inhibition and an intact eosinophil compartment.

Fernandes S, Srivastava N, Pedicone C, Sudan R, Luke EA, Dungan OM, Pacherille A, Meyer ST, Dormann S, Schurmans S, Chambers BJ, Chisholm JD, Kerr WG. Fernandes S, et al. Among authors: pedicone c. iScience. 2023 Jan 28;26(2):106071. doi: 10.1016/j.isci.2023.106071. eCollection 2023 Feb 17. iScience. 2023. PMID: 36818285 Free PMC article.

7

Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus.

Matera A, Compagnion AC, Pedicone C, Kotah JM, Ivanov A, Monsorno K, Labouèbe G, Leggio L, Pereira-Iglesias M, Beule D, Mansuy-Aubert V, Williams TL, Iraci N, Sierra A, Marro SG, Goate AM, Eggen BJL, Kerr WG, Paolicelli RC. Matera A, et al. Among authors: pedicone c. Immunity. 2024 Dec 9:S1074-7613(24)00513-2. doi: 10.1016/j.immuni.2024.11.003. Online ahead of print. Immunity. 2024. PMID: 39657671 Free article.

8

Development of MAPT S305 mutation human iPSC lines exhibiting elevated 4R tau expression and functional alterations in neurons and astrocytes.

Bowles KR, Pedicone C, Pugh DA, Oja LM, Sousa FH, Keavey LK, Fulton-Howard B, Weitzman SA, Liu Y, Chen JL, Disney MD, Goate AM. Bowles KR, et al. Among authors: pedicone c. Cell Rep. 2024 Dec 24;43(12):115013. doi: 10.1016/j.celrep.2024.115013. Epub 2024 Nov 27. Cell Rep. 2024. PMID: 39602304 Free article.

9

Unraveling the complex role of MAPT-containing H1 and H2 haplotypes in neurodegenerative diseases.

Pedicone C, Weitzman SA, Renton AE, Goate AM. Pedicone C, et al. Mol Neurodegener. 2024 May 29;19(1):43. doi: 10.1186/s13024-024-00731-x. Mol Neurodegener. 2024. PMID: 38812061 Free PMC article. Review.

10

SHIP inhibition mediates select TREM2-induced microglial functions.

Ramakrishnan GS, Berry WL, Pacherille A, Kerr WG, Chisholm JD, Pedicone C, Humphrey MB. Ramakrishnan GS, et al. Among authors: pedicone c. Mol Immunol. 2024 Jun;170:35-45. doi: 10.1016/j.molimm.2024.04.002. Epub 2024 Apr 12. Mol Immunol. 2024. PMID: 38613944 Free article.

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