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Regulation of OATP1B1 Function by Tyrosine Kinase-mediated Phosphorylation.
Hayden ER, Chen M, Pasquariello KZ, Gibson AA, Petti JJ, Shen S, Qu J, Ong SS, Chen T, Jin Y, Uddin ME, Huang KM, Paz A, Sparreboom A, Hu S, Sprowl JA. Hayden ER, et al. Among authors: chen m, chen t. Clin Cancer Res. 2021 Aug 1;27(15):4301-4310. doi: 10.1158/1078-0432.CCR-21-0023. Epub 2021 Mar 4. Clin Cancer Res. 2021. PMID: 33664059 Free PMC article.
Role of CAR and PXR in xenobiotic sensing and metabolism.
Wang YM, Ong SS, Chai SC, Chen T. Wang YM, et al. Among authors: chen t. Expert Opin Drug Metab Toxicol. 2012 Jul;8(7):803-17. doi: 10.1517/17425255.2012.685237. Epub 2012 May 3. Expert Opin Drug Metab Toxicol. 2012. PMID: 22554043 Free PMC article. Review.
Serine 350 of human pregnane X receptor is crucial for its heterodimerization with retinoid X receptor alpha and transactivation of target genes in vitro and in vivo.
Wang YM, Chai SC, Lin W, Chai X, Elias A, Wu J, Ong SS, Pondugula SR, Beard JA, Schuetz EG, Zeng S, Xie W, Chen T. Wang YM, et al. Among authors: chen t. Biochem Pharmacol. 2015 Aug 15;96(4):357-68. doi: 10.1016/j.bcp.2015.06.018. Epub 2015 Jun 25. Biochem Pharmacol. 2015. PMID: 26119819 Free PMC article.
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