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Ki-67 regulates global gene expression and promotes sequential stages of carcinogenesis.
Mrouj K, Andrés-Sánchez N, Dubra G, Singh P, Sobecki M, Chahar D, Al Ghoul E, Aznar AB, Prieto S, Pirot N, Bernex F, Bordignon B, Hassen-Khodja C, Villalba M, Krasinska L, Fisher D. Mrouj K, et al. Among authors: aznar ab. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2026507118. doi: 10.1073/pnas.2026507118. Proc Natl Acad Sci U S A. 2021. PMID: 33658388 Free PMC article.
ODZ1 allows glioblastoma to sustain invasiveness through a Myc-dependent transcriptional upregulation of RhoA.
Talamillo A, Grande L, Ruiz-Ontañon P, Velasquez C, Mollinedo P, Torices S, Sanchez-Gomez P, Aznar A, Esparis-Ogando A, Lopez-Lopez C, Lafita C, Berciano MT, Montero JA, Vazquez-Barquero A, Segura V, Villagra NT, Pandiella A, Lafarga M, Leon J, Martinez-Climent JA, Sanz-Moreno V, Fernandez-Luna JL. Talamillo A, et al. Oncogene. 2017 Mar 23;36(12):1733-1744. doi: 10.1038/onc.2016.341. Epub 2016 Sep 19. Oncogene. 2017. PMID: 27641332