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Chromothripsis drives the evolution of gene amplification in cancer.
Shoshani O, Brunner SF, Yaeger R, Ly P, Nechemia-Arbely Y, Kim DH, Fang R, Castillon GA, Yu M, Li JSZ, Sun Y, Ellisman MH, Ren B, Campbell PJ, Cleveland DW. Shoshani O, et al. Nature. 2021 Mar;591(7848):137-141. doi: 10.1038/s41586-020-03064-z. Epub 2020 Dec 23. Nature. 2021. PMID: 33361815 Free PMC article.
Gene expression regulated by RNA stability.
Shoshani O, Cleveland DW. Shoshani O, et al. Science. 2020 Jan 3;367(6473):29. doi: 10.1126/science.aba0713. Science. 2020. PMID: 31896707 No abstract available.
Transient genomic instability drives tumorigenesis through accelerated clonal evolution.
Shoshani O, Bakker B, de Haan L, Tijhuis AE, Wang Y, Kim DH, Maldonado M, Demarest MA, Artates J, Zhengyu O, Mark A, Wardenaar R, Sasik R, Spierings DCJ, Vitre B, Fisch K, Foijer F, Cleveland DW. Shoshani O, et al. Genes Dev. 2021 Aug 1;35(15-16):1093-1108. doi: 10.1101/gad.348319.121. Epub 2021 Jul 15. Genes Dev. 2021. PMID: 34266887 Free PMC article.
Chronic centrosome amplification without tumorigenesis.
Vitre B, Holland AJ, Kulukian A, Shoshani O, Hirai M, Wang Y, Maldonado M, Cho T, Boubaker J, Swing DA, Tessarollo L, Evans SM, Fuchs E, Cleveland DW. Vitre B, et al. Among authors: shoshani o. Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):E6321-30. doi: 10.1073/pnas.1519388112. Epub 2015 Nov 2. Proc Natl Acad Sci U S A. 2015. PMID: 26578792 Free PMC article.
Stress as a fundamental theme in cell plasticity.
Shoshani O, Zipori D. Shoshani O, et al. Biochim Biophys Acta. 2015 Apr;1849(4):371-7. doi: 10.1016/j.bbagrm.2014.07.006. Epub 2014 Jul 16. Biochim Biophys Acta. 2015. PMID: 25038585 Review.
56 results