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Evidence that GPVI is Expressed as a Mixture of Monomers and Dimers, and that the D2 Domain is not Essential for GPVI Activation.
Clark JC, Neagoe RAI, Zuidscherwoude M, Kavanagh DM, Slater A, Martin EM, Soave M, Stegner D, Nieswandt B, Poulter NS, Hummert J, Herten DP, Tomlinson MG, Hill SJ, Watson SP. Clark JC, et al. Among authors: hill sj. Thromb Haemost. 2021 Nov;121(11):1435-1447. doi: 10.1055/a-1401-5014. Epub 2021 Apr 14. Thromb Haemost. 2021. PMID: 33638140
A monoclonal antibody raised against a thermo-stabilised β1-adrenoceptor interacts with extracellular loop 2 and acts as a negative allosteric modulator of a sub-set of β1-adrenoceptors expressed in stable cell lines.
Soave M, Cseke G, Hutchings CJ, Brown AJH, Woolard J, Hill SJ. Soave M, et al. Among authors: hill sj. Biochem Pharmacol. 2018 Jan;147:38-54. doi: 10.1016/j.bcp.2017.10.015. Epub 2017 Nov 2. Biochem Pharmacol. 2018. PMID: 29102678 Free PMC article.
Fluorescent ligands: Bringing light to emerging GPCR paradigms.
Soave M, Briddon SJ, Hill SJ, Stoddart LA. Soave M, et al. Among authors: hill sj. Br J Pharmacol. 2020 Mar;177(5):978-991. doi: 10.1111/bph.14953. Epub 2020 Feb 6. Br J Pharmacol. 2020. PMID: 31877233 Free PMC article. Review.
463 results