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494 results

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Page 1
Combinatorial CRISPR screen identifies fitness effects of gene paralogues.
Thompson NA, Ranzani M, van der Weyden L, Iyer V, Offord V, Droop A, Behan F, Gonçalves E, Speak A, Iorio F, Hewinson J, Harle V, Robertson H, Anderson E, Fu B, Yang F, Zagnoli-Vieira G, Chapman P, Del Castillo Velasco-Herrera M, Garnett MJ, Jackson SP, Adams DJ. Thompson NA, et al. Among authors: jackson sp. Nat Commun. 2021 Feb 26;12(1):1302. doi: 10.1038/s41467-021-21478-9. Nat Commun. 2021. PMID: 33637726 Free PMC article.
Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.
McIntyre RE, Lakshminarasimhan Chavali P, Ismail O, Carragher DM, Sanchez-Andrade G, Forment JV, Fu B, Del Castillo Velasco-Herrera M, Edwards A, van der Weyden L, Yang F; Sanger Mouse Genetics Project; Ramirez-Solis R, Estabel J, Gallagher FA, Logan DW, Arends MJ, Tsang SH, Mahajan VB, Scudamore CL, White JK, Jackson SP, Gergely F, Adams DJ. McIntyre RE, et al. Among authors: jackson sp. PLoS Genet. 2012;8(11):e1003022. doi: 10.1371/journal.pgen.1003022. Epub 2012 Nov 15. PLoS Genet. 2012. PMID: 23166506 Free PMC article.
Synthetic viability genomic screening defines Sae2 function in DNA repair.
Puddu F, Oelschlaegel T, Guerini I, Geisler NJ, Niu H, Herzog M, Salguero I, Ochoa-Montaño B, Viré E, Sung P, Adams DJ, Keane TM, Jackson SP. Puddu F, et al. Among authors: jackson sp. EMBO J. 2015 Jun 3;34(11):1509-22. doi: 10.15252/embj.201590973. Epub 2015 Apr 21. EMBO J. 2015. PMID: 25899817 Free PMC article.
Synthetic lethality between PAXX and XLF in mammalian development.
Balmus G, Barros AC, Wijnhoven PW, Lescale C, Hasse HL, Boroviak K, le Sage C, Doe B, Speak AO, Galli A, Jacobsen M, Deriano L, Adams DJ, Blackford AN, Jackson SP. Balmus G, et al. Among authors: jackson sp. Genes Dev. 2016 Oct 1;30(19):2152-2157. doi: 10.1101/gad.290510.116. Genes Dev. 2016. PMID: 27798842 Free PMC article.
Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia.
Moder M, Velimezi G, Owusu M, Mazouzi A, Wiedner M, Ferreira da Silva J, Robinson-Garcia L, Schischlik F, Slavkovsky R, Kralovics R, Schuster M, Bock C, Ideker T, Jackson SP, Menche J, Loizou JI. Moder M, et al. Among authors: jackson sp. Nat Commun. 2017 Nov 1;8(1):1238. doi: 10.1038/s41467-017-01439-x. Nat Commun. 2017. PMID: 29089570 Free PMC article.
Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome.
Balmus G, Larrieu D, Barros AC, Collins C, Abrudan M, Demir M, Geisler NJ, Lelliott CJ, White JK, Karp NA, Atkinson J, Kirton A, Jacobsen M, Clift D, Rodriguez R; Sanger Mouse Genetics Project; Adams DJ, Jackson SP. Balmus G, et al. Among authors: jackson sp. Nat Commun. 2018 Apr 27;9(1):1700. doi: 10.1038/s41467-018-03770-3. Nat Commun. 2018. PMID: 29703891 Free PMC article.
494 results