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Page 1
Combinatorial CRISPR screen identifies fitness effects of gene paralogues.
Thompson NA, Ranzani M, van der Weyden L, Iyer V, Offord V, Droop A, Behan F, Gonçalves E, Speak A, Iorio F, Hewinson J, Harle V, Robertson H, Anderson E, Fu B, Yang F, Zagnoli-Vieira G, Chapman P, Del Castillo Velasco-Herrera M, Garnett MJ, Jackson SP, Adams DJ. Thompson NA, et al. Among authors: droop a. Nat Commun. 2021 Feb 26;12(1):1302. doi: 10.1038/s41467-021-21478-9. Nat Commun. 2021. PMID: 33637726 Free PMC article.
Analysis of CRISPR-Cas9 screens identifies genetic dependencies in melanoma.
Christodoulou E, Rashid M, Pacini C, Droop A, Robertson H, Groningen TV, Teunisse AFAS, Iorio F, Jochemsen AG, Adams DJ, Doorn RV. Christodoulou E, et al. Among authors: droop a. Pigment Cell Melanoma Res. 2021 Jan;34(1):122-131. doi: 10.1111/pcmr.12919. Epub 2020 Sep 7. Pigment Cell Melanoma Res. 2021. PMID: 32767816 Free PMC article.
The mutational signature profile of known and suspected human carcinogens in mice.
Riva L, Pandiri AR, Li YR, Droop A, Hewinson J, Quail MA, Iyer V, Shepherd R, Herbert RA, Campbell PJ, Sills RC, Alexandrov LB, Balmain A, Adams DJ. Riva L, et al. Among authors: droop a. Nat Genet. 2020 Nov;52(11):1189-1197. doi: 10.1038/s41588-020-0692-4. Epub 2020 Sep 28. Nat Genet. 2020. PMID: 32989322 Free PMC article.
CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation.
van der Weyden L, Harle V, Turner G, Offord V, Iyer V, Droop A, Swiatkowska A, Rabbie R, Campbell AD, Sansom OJ, Pardo M, Choudhary JS, Ferreira I, Tullett M, Arends MJ, Speak AO, Adams DJ. van der Weyden L, et al. Among authors: droop a. Commun Biol. 2021 Mar 23;4(1):395. doi: 10.1038/s42003-021-01912-w. Commun Biol. 2021. PMID: 33758365 Free PMC article.
The clinicopathologic spectrum and genomic landscape of de-/trans-differentiated melanoma.
Ferreira I, Droop A, Edwards O, Wong K, Harle V, Habeeb O, Gharpuray-Pandit D, Houghton J, Wiedemeyer K, Mentzel T, Billings SD, Ko JS, Füzesi L, Mulholland K, Prusac IK, Liegl-Atzwanger B, de Saint Aubain N, Caldwell H, Riva L, van der Weyden L, Arends MJ, Brenn T, Adams DJ. Ferreira I, et al. Among authors: droop a. Mod Pathol. 2021 Nov;34(11):2009-2019. doi: 10.1038/s41379-021-00857-z. Epub 2021 Jun 21. Mod Pathol. 2021. PMID: 34155350 Free article.
Defining novel causal SNPs and linked phenotypes at melanoma-associated loci.
Castaneda-Garcia C, Iyer V, Nsengimana J, Trower A, Droop A, Brown KM, Choi J, Zhang T, Harland M, Newton-Bishop JA, Bishop DT, Adams DJ, Iles MM, Robles-Espinoza CD. Castaneda-Garcia C, et al. Among authors: droop a. Hum Mol Genet. 2022 Aug 25;31(17):2845-2856. doi: 10.1093/hmg/ddac074. Hum Mol Genet. 2022. PMID: 35357426 Free PMC article.
Comprehensive mutational profiling identifies new driver events in cutaneous leiomyosarcoma.
van der Weyden L, Del Castillo Velasco-Herrera M, Cheema S, Wong K, Boccacino JM, Offord V, Droop A, Jones DRA, Vermes I, Anderson E, Hardy C, de Saint Aubain N, Ferguson PM, Clarke EL, Merchant W, Mogler C, Frew D, Harms PW, Monteagudo C, Billings SD, Arends MJ, Ferreira I, Brenn T, J Adams D. van der Weyden L, et al. Among authors: droop a. Br J Dermatol. 2024 Oct 11:ljae386. doi: 10.1093/bjd/ljae386. Online ahead of print. Br J Dermatol. 2024. PMID: 39392932
Exploration of the mutational landscape of cutaneous leiomyoma confirms FH as a driver gene and identifies targeting purine metabolism as a potential therapeutic strategy.
van der Weyden L, Del Castillo Velasco-Herrera M, Cheema S, Wong K, Boccacino JM, Vermes I, Offord V, Droop A, Jones DRA, Anderson E, Hardy C, de Saint Aubain N, Ferguson PM, Mogler C, Rajan N, Frew D, Harms PW, Billings SD, Schatton D, Segarra-Mondejar M, Arends MJ, Ferreira I, Brenn T, Frezza C, Adams DJ. van der Weyden L, et al. Among authors: droop a. Br J Dermatol. 2024 Nov 7:ljae432. doi: 10.1093/bjd/ljae432. Online ahead of print. Br J Dermatol. 2024. PMID: 39506538 No abstract available.
56 results